Disruption of E-cadherin by matrix metalloproteinase directly mediates epithelial-mesenchymal transition downstream of transforming growth factor-β1 in renal tubular …

G Zheng, JG Lyons, TK Tan, Y Wang, TT Hsu… - The American journal of …, 2009 - Elsevier
Epithelial-mesenchymal transition (EMT) plays an important role in organ fibrosis, including
that of the kidney. Loss of E-cadherin expression is a hallmark of EMT; however, whether the …

Matrix metalloproteinase-9 of tubular and macrophage origin contributes to the pathogenesis of renal fibrosis via macrophage recruitment through osteopontin …

T Kui Tan, G Zheng, TT Hsu, S Ra Lee, J Zhang… - Laboratory …, 2013 - nature.com
A pro-fibrotic role of matrix metalloproteinase-9 (MMP-9) in tubular cell epithelial–mesenchymal
transition (EMT) is well established in renal fibrosis; however studies from our group and …

[HTML][HTML] Macrophage matrix metalloproteinase-9 mediates epithelial-mesenchymal transition in vitro in murine renal tubular cells

TK Tan, G Zheng, TT Hsu, Y Wang, VWS Lee… - The American journal of …, 2010 - Elsevier
As a rich source of pro-fibrogenic growth factors and matrix metalloproteinases (MMPs),
macrophages are well-placed to play an important role in renal fibrosis. However, the exact …

Optimal performance and emissions of diesel/hydrogen-rich gas engine varying intake air temperature and EGR ratio

HW Wu, TT Hsu, JY He, CM Fan - Applied Thermal Engineering, 2017 - Elsevier
Having integrated intake air heating system, a steam reforming system, and cooled EGR
system into a diesel/hydrogen-rich gas engine, the authors applied the Taguchi approach to …

Reduction of smoke, PM2. 5, and NOX of a diesel engine integrated with methanol steam reformer recovering waste heat and cooled EGR

HW Wu, TT Hsu, CM Fan, PH He - Energy Conversion and Management, 2018 - Elsevier
Over recent years, combustion engines are effectively equipped with a waste heat recovery (WHR)
system to produce power or hydrogen at less additional energy input. The WHR …

[HTML][HTML] α3 integrin of cell-cell contact mediates kidney fibrosis by integrin-linked kinase in proximal tubular E-cadherin deficient mice

…, H Wang, M Pang, X Qiao, SR Lee, TT Hsu… - The American journal of …, 2016 - Elsevier
Loss of E-cadherin marks a defect in epithelial integrity and polarity during tissue injury and
fibrosis. Whether loss of E-cadherin plays a causal role in fibrosis is uncertain. α3β1 Integrin …

Optimal factors estimation for diesel/methanol engines changing methanol injection timing and inlet air temperature

HW Wu, CM Fan, JY He, TT Hsu - Energy, 2017 - Elsevier
Methanol has been injected at the intake port with heated inlet air in a diesel engine. In the
meantime, the Taguchi methodology was adopted to estimate the optimal methanol-energy-…

Personal research idea recommendation using research trends and a hierarchical topic model

HC Wang, TT Hsu, Y Sari - Scientometrics, 2019 - Springer
In the era of rapid technological advance, it is an important task for all researchers to keep up
with trends when performing research. How to efficiently find suitable research topics while …

Biomechanical implications of an oblique knee joint line

JM Hooper, P Walker, TT Hsu, A Kurtz… - The Journal of Knee …, 2018 - thieme-connect.com
Surgical correction of multiapical deformities of the lower limb requires careful preoperative
planning. Surgeons must account for the potential creation of secondary deformity, such as …

Genotypes of cancer stem cells characterized by epithelial-to-mesenchymal transition and proliferation related functions

CL Hsu, FH Chung, CH Chen, TT Hsu, SM Liu… - Scientific Reports, 2016 - nature.com
Cancer stem cells (CSCs), or cancer cells with stem cell-like properties, generally exhibit drug
resistance and have highly potent cancer inducing capabilities. Genome-wide expression …