User profiles for Tian Fu

Tian-Min Fu

- Verified email at crystal.harvard.edu - Cited by 3664

Tian-Ming Fu

- Verified email at princeton.edu - Cited by 3654

Oxidative stress: placenta function and dysfunction

F Wu, FJ Tian, Y Lin, WM Xu - American journal of reproductive …, 2016 - Wiley Online Library
During pregnancy, the placenta is a site of active oxygen metabolism that continuously
generates oxidative stress ( OS ). Overproduction of reactive oxygen species and reactive …

Oxidative stress in placenta: health and diseases

F Wu, FJ Tian, Y Lin - BioMed research international, 2015 - Wiley Online Library
During pregnancy, development of the placenta is interrelated with the oxygen concentration.
Embryo development takes place in a low oxygen environment until the beginning of the …

Structural biology of innate immunity

Q Yin, TM Fu, J Li, H Wu - Annual review of immunology, 2015 - annualreviews.org
Innate immune responses depend on timely recognition of pathogenic or danger signals by
multiple cell surface or cytoplasmic receptors and transmission of signals for proper …

Gasdermin D pore structure reveals preferential release of mature interleukin-1

…, JL Pablo, Y Dong, SM Vora, L Wang, TM Fu… - Nature, 2021 - nature.com
As organelles of the innate immune system, inflammasomes activate caspase-1 and other
inflammatory caspases that cleave gasdermin D (GSDMD). Caspase-1 also cleaves inactive …

Three-dimensional macroporous nanoelectronic networks as minimally invasive brain probes

C Xie, J Liu, TM Fu, X Dai, W Zhou, CM Lieber - Nature materials, 2015 - nature.com
Direct electrical recording and stimulation of neural activity using micro-fabricated silicon
and metal micro-wire probes have contributed extensively to basic neuroscience and …

Structure of cytoplasmic ring of nuclear pore complex by integrative cryo-EM and AlphaFold

…, Y Dong, X Pi, AB Tong, CW Hecksel, L Wang, TM Fu… - Science, 2022 - science.org
INTRODUCTION The nuclear pore complex (NPC) is the molecular conduit in the nuclear
membrane of eukaryotic cells that regulates import and export of biomolecules between the …

Bioinspired neuron-like electronics

…, TJ Zwang, G Hong, Y Zhao, RD Viveros, TM Fu… - Nature materials, 2019 - nature.com
As an important application of functional biomaterials, neural probes have contributed
substantially to studying the brain. Bioinspired and biomimetic strategies have begun to be …

Stable long-term chronic brain mapping at the single-neuron level

TM Fu, G Hong, T Zhou, TG Schuhmann, RD Viveros… - Nature …, 2016 - nature.com
Stable in vivo mapping and modulation of the same neurons and brain circuits over extended
periods is critical to both neuroscience and medicine. Current electrical implants offer …

[HTML][HTML] Phase separation drives RNA virus-induced activation of the NLRP6 inflammasome

…, TM Fu, A Wang, K He, L Andreeva, P Gao, Z Tian… - Cell, 2021 - cell.com
NLRP6 is important in host defense by inducing functional outcomes including inflammasome
activation and interferon production. Here, we show that NLRP6 undergoes liquid-liquid …

General strategy for biodetection in high ionic strength solutions using transistor-based nanoelectronic sensors

N Gao, W Zhou, X Jiang, G Hong, TM Fu, CM Lieber - Nano letters, 2015 - ACS Publications
Transistor-based nanoelectronic sensors are capable of label-free real-time chemical and
biological detection with high sensitivity and spatial resolution, although the short Debye …