Recent development of optimization of lyophilization process
H Kawasaki, T Shimanouchi, Y Kimura - Journal of chemistry, 2019 - Wiley Online Library
The objective of this review is to survey the development of the optimization of lyophilization.
The optimization study of the lyophilizer has been roughly developing by the order of (i) trial…
The optimization study of the lyophilizer has been roughly developing by the order of (i) trial…
Calcein permeation across phosphatidylcholine bilayer membrane: Effects of membrane fluidity, liposome size, and immobilization
T Shimanouchi, H Ishii, N Yoshimoto… - Colloids and Surfaces B …, 2009 - Elsevier
The permeation of calcein across the phospholipid bilayer membrane is a key phenomenon
in the detection system using liposomes as a sensor unit. The behavior of the calcein …
in the detection system using liposomes as a sensor unit. The behavior of the calcein …
Chemical conversion and liquid–liquid extraction of 5‐hydroxymethylfurfural from fructose by slug flow microreactor
T Shimanouchi, Y Kataoka, T Tanifuji, Y Kimura… - AIChE …, 2016 - Wiley Online Library
A dehydration of fructose in the water/methyl isobuthyl ketone (MIBK) biphasic system can
yield 5‐hydroxymethylfurfural (HMF) to be successfully extracted into the organic MIBK phase. …
yield 5‐hydroxymethylfurfural (HMF) to be successfully extracted into the organic MIBK phase. …
Sulfated glycosaminoglycans mediate prion-like behavior of p53 aggregates
…, H Saito, Y Ihara, T Shimanouchi… - Proceedings of the …, 2020 - National Acad Sciences
Sulfated glycosaminoglycans (GAGs) such as heparan sulfate (HS) are heteropolysaccharides
implicated in the pathology of protein aggregation diseases including localized and …
implicated in the pathology of protein aggregation diseases including localized and …
Classification of binding property of amyloid β to lipid membranes: Membranomic research using quartz crystal microbalance combined with the immobilization of lipid …
T Shimanouchi, M Iwamura, Y Sano, K Hayashi… - … et Biophysica Acta (BBA …, 2024 - Elsevier
… Shimanouchi et al. have defined the acqirement of the above information based on the
liposome… Toshinori Shimanouchi and Minoru Noda report financial support was provided by JSPS …
liposome… Toshinori Shimanouchi and Minoru Noda report financial support was provided by JSPS …
Kinetic study on giant vesicle formation with electroformation method
T Shimanouchi, H Umakoshi, R Kuboi - Langmuir, 2009 - ACS Publications
Giant vesicles (GVs) composed of zwitterionic phospholipids were prepared by the
electroformation method. The growth behavior of GVs was quantitatively analyzed as a first-order …
electroformation method. The growth behavior of GVs was quantitatively analyzed as a first-order …
Mechanisms of enhanced aggregation and fibril formation of Parkinson's disease-related variants of α-synuclein
T Ohgita, N Namba, H Kono, T Shimanouchi, H Saito - Scientific reports, 2022 - nature.com
Aggregation of α-synuclein (α-syn) into amyloid fibrils is closely associated with Parkinson’s
disease (PD). Familial mutations or posttranslational truncations in α-syn are known as risk …
disease (PD). Familial mutations or posttranslational truncations in α-syn are known as risk …
Intramolecular interaction kinetically regulates fibril formation by human and mouse α-synuclein
T Ohgita, H Kono, I Morita, H Oyama, T Shimanouchi… - Scientific reports, 2023 - nature.com
Regulation of α-synuclein (αS) fibril formation is a potent therapeutic strategy for αS-related
neurodegenerative disorders. αS, an intrinsically disordered 140-residue intraneural protein, …
neurodegenerative disorders. αS, an intrinsically disordered 140-residue intraneural protein, …
Span 80 vesicles have a more fluid, flexible and “wet” surface than phospholipid liposomes
K Hayashi, T Shimanouchi, K Kato, T Miyazaki… - Colloids and Surfaces B …, 2011 - Elsevier
The surface properties of Span 80 vesicles at various cholesterol contents, together with
those of various liposomes, were characterized by using fluorescence probes. The membrane …
those of various liposomes, were characterized by using fluorescence probes. The membrane …
Elevating the fuel properties of Humulus lupulus, Plumeria alba and Calophyllum inophyllum L. through wet torrefaction
W Yang, T Shimanouchi, M Iwamura, Y Takahashi… - Fuel, 2015 - Elsevier
Wet torrefaction is an effective process to improve the fuel properties of a biomass. However,
different biomasses have different component weight ratios and it is possible that not all …
different biomasses have different component weight ratios and it is possible that not all …