Long non-coding RNA HOTAIR in circulatory exosomes is correlated with ErbB2/HER2 positivity in breast cancer

YL Wang, LC Liu, Y Hung, CJ Chen, YZ Lin, WR Wu… - The Breast, 2019 - Elsevier
Cancer cells are known to produce and secret extracellular vesicles for intercellular
communication through the carried cargos. HOTAIR (HOX transcript antisense intergenic RNA), a …

[HTML][HTML] The functions of PCNA in tumor stemness and invasion

YL Wang, WR Wu, PL Lin, YC Shen, YZ Lin… - International Journal of …, 2022 - mdpi.com
Invasion is the most prominent lethal feature of malignant cancer. However, how cell proliferation,
another important feature of tumor development, is integrated with tumor invasion and …

mTOR signaling in the nucleus accumbens mediates behavioral sensitization to methamphetamine

SH Huang, WR Wu, LM Lee, PR Huang… - Progress in Neuro …, 2018 - Elsevier
Chronic psychostimulant treatment in rodents readily produces behavioral sensitization,
which reflects altered brain function in response to repeated drug exposure. Numerous …

[HTML][HTML] Evading immune surveillance via tyrosine phosphorylation of nuclear PCNA

YL Wang, CC Lee, YC Shen, PL Lin, WR Wu, YZ Lin… - Cell reports, 2021 - cell.com
Increased DNA replication and metastasis are hallmarks of cancer progression, while
deregulated proliferation often triggers sustained replication stresses in cancer cells. How cancer …

Simultaneous optimization of analog circuits with reliability and variability for applications on flexible electronics

YL Chen, WR Wu, CNJ Liu… - IEEE Transactions on …, 2013 - ieeexplore.ieee.org
Flexible electronics are a possible alternative for portable consumer applications and have
many advantages. However, the circuit design for flexible electronics is still challenging, …

[HTML][HTML] Memory-promoting function of miR-379-5p attenuates CD8+ T cell exhaustion by targeting immune checkpoints

YZ Lin, CH Liu, WR Wu, TY Liao… - Journal for …, 2025 - pmc.ncbi.nlm.nih.gov
Background MicroRNAs (miRNAs) are epigenetic regulators of T cell maturation and
exhaustion. However, the mechanisms by which miRNAs influence T cell function in tumor …

Growth-promoting function of the cGAS-STING pathway in triple-negative breast cancer cells

LC Liu, YC Shen, YL Wang, WR Wu, LC Chang… - Frontiers in …, 2022 - frontiersin.org
The cGAS-STING axis is one of the key mechanisms guarding cells from pathogen invasion
in the cytoplasmic compartment. Sensing of foreign DNA in the cytosol by the cGAS-STING …

[HTML][HTML] Imatinib (STI571) inhibits the expression of angiotensin-converting enzyme 2 and cell entry of the SARS-CoV-2-derived pseudotyped viral particles

YZ Lin, YC Shen, WR Wu, WJ Wang, YL Wang… - International Journal of …, 2021 - mdpi.com
A group of clinically approved cancer therapeutic tyrosine kinase inhibitors was screened to
test their effects on the expression of angiotensin-converting enzyme 2 (ACE2), the cell …

Improvement of sentiment analysis via re-evaluation of objective words in SenticNet for hotel reviews

C Hung, WR Wu, HM Chou - Language Resources and Evaluation, 2021 - Springer
In order to extract the correct sentiment polarity from word of mouth (WOM), a wide-scale
and well-organized sentiment lexicon is generally beneficial. SenticNet is one such lexicon. …

[HTML][HTML] miR-4759 suppresses breast cancer through immune checkpoint blockade

YZ Lin, SH Liu, WR Wu, YC Shen, YL Wang… - Computational and …, 2022 - Elsevier
Programmed cell death protein 1 (PD-1)/ programmed cell death protein ligand 1 (PD-L1) is
the key immune checkpoint governing evasion of advanced cancer from immune …