Heart repair by reprogramming non-myocytes with cardiac transcription factors
K Song, YJ Nam, X Luo, X Qi, W Tan, GN Huang… - Nature, 2012 - nature.com
The adult mammalian heart possesses little regenerative potential following injury. Fibrosis
due to activation of cardiac fibroblasts impedes cardiac regeneration and contributes to loss …
due to activation of cardiac fibroblasts impedes cardiac regeneration and contributes to loss …
Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL–RANK signalling
W Tan, W Zhang, A Strasner, S Grivennikov, JQ Cheng… - Nature, 2011 - nature.com
Inflammatory mechanisms influence tumorigenesis and metastatic progression even in cancers
whose aetiology does not involve pre-existing inflammation or infection, such as breast …
whose aetiology does not involve pre-existing inflammation or infection, such as breast …
Macrophages are required for neonatal heart regeneration
AB Aurora, ER Porrello, W Tan, AI Mahmoud… - The Journal of clinical …, 2014 - jci.org
Myocardial infarction (MI) leads to cardiomyocyte death, which triggers an immune response
that clears debris and restores tissue integrity. In the adult heart, the immune system …
that clears debris and restores tissue integrity. In the adult heart, the immune system …
[HTML][HTML] Mussel-inspired polydopamine for bio-surface functionalization
Surface functionalization via molecular design has been a key approach to incorporate new
functionalities into existing biomaterials for biomedical application. Mussel-inspired …
functionalities into existing biomaterials for biomedical application. Mussel-inspired …
Process mining manifesto
Process mining techniques are able to extract knowledge from event logs commonly available
in today’s information systems. These techniques provide new means to discover, monitor…
in today’s information systems. These techniques provide new means to discover, monitor…
[BOOK][B] Shallow water hydrodynamics: Mathematical theory and numerical solution for a two-dimensional system of shallow-water equations
WY Tan - 1992 - books.google.com
Within this monograph a comprehensive and systematic knowledge on shallow-water
hydrodynamics is presented. A two-dimensional system of shallow-water equations is analyzed, …
hydrodynamics is presented. A two-dimensional system of shallow-water equations is analyzed, …
A trap-and-release integrated microfluidic system for dynamic microarray applications
WH Tan, S Takeuchi - Proceedings of the national academy of sciences, 2007 - pnas.org
Dynamic microarrays hold great promise for advancing research in proteomics, diagnostics
and drug discovery. However, this potential has yet to be fully realized due to the lack of …
and drug discovery. However, this potential has yet to be fully realized due to the lack of …
Hippo pathway effector Yap promotes cardiac regeneration
…, J McAnally, ER Porrello, AI Mahmoud, W Tan… - Proceedings of the …, 2013 - pnas.org
The adult mammalian heart has limited potential for regeneration. Thus, after injury,
cardiomyocytes are permanently lost, and contractility is diminished. In contrast, the neonatal heart …
cardiomyocytes are permanently lost, and contractility is diminished. In contrast, the neonatal heart …
[HTML][HTML] Antimicrobial peptides from plants
Plant antimicrobial peptides (AMPs) have evolved differently from AMPs from other life forms.
They are generally rich in cysteine residues which form multiple disulfides. In turn, the …
They are generally rich in cysteine residues which form multiple disulfides. In turn, the …
Overview of multiplex immunohistochemistry/immunofluorescence techniques in the era of cancer immunotherapy
WCC Tan, SN Nerurkar, HY Cai, HHM Ng… - Cancer …, 2020 - Wiley Online Library
Conventional immunohistochemistry (IHC) is a widely used diagnostic technique in tissue
pathology. However, this technique is associated with a number of limitations, including high …
pathology. However, this technique is associated with a number of limitations, including high …