Osteosarcoma is the most common nonhematologic malignancy of bone in children and adults.
The peak incidence occurs in the second decade of life, with a smaller peak after age 50. …

Objective Mild cognitive impairment (MCI) is a preclinical and transitional stage between
healthy ageing and dementia. The purpose of our study was to investigate the recent pooled …

Wnt signaling plays an important role in regulating cell proliferation and differentiation. De-regulation
of these signaling pathways has been implicated in many human diseases, …

Recombinant adenoviruses provide a versatile system for gene expression studies and
therapeutic applications. We have developed an approach that simplifies the generation and …

Efficacious bone regeneration could revolutionize the clinical management of many bone
and musculoskeletal disorders. Bone morphogenetic proteins (BMPs) can regulate the …

Pluripotent mesenchymal stem cells (MSCs) are bone marrow stromal progenitor cells that
can differentiate into osteogenic, chondrogenic, adipogenic, and myogenic lineages. Several …

Bone morphogenetic protein 9 (BMP‐9) is a member of the transforming growth factor (TGF)‐β/BMP
superfamily, and we have demonstrated that it is one of the most potent BMPs to …

Marrow mesenchymal stem cells are pluripotent progenitors that can differentiate into bone,
cartilage, muscle, and fat cells. Wnt signaling has been implicated in regulating osteogenic …

Osteosarcoma (OS) is the most common primary malignancy of bone. Here, we investigated
a possible role of defective osteoblast differentiation in OS tumorigenesis. We found that …

This study was designed to determine the changes in saponin content in American ginseng
berries after treatment by heating and to assess the anticancer effects of the extracts. After …