Liquid-liquid phase separation in biology: mechanisms, physiological functions and human diseases
Cells are compartmentalized by numerous membrane-enclosed organelles and membraneless
compartments to ensure that a wide variety of cellular activities occur in a spatially and …
compartments to ensure that a wide variety of cellular activities occur in a spatially and …
[HTML][HTML] Myosin VI undergoes cargo-mediated dimerization
Myosin VI is the only known molecular motor that moves toward the minus ends of actin
filaments; thus, it plays unique roles in diverse cellular processes. The processive walking of …
filaments; thus, it plays unique roles in diverse cellular processes. The processive walking of …
Autoinhibition of UNC5b revealed by the cytoplasmic domain structure of the receptor
The cytoplasmic domains of UNC5 are responsible for its netrin-mediated signaling events
in axonal migrations, blood vessel patterning, and apoptosis, although the molecular …
in axonal migrations, blood vessel patterning, and apoptosis, although the molecular …
[HTML][HTML] LGN/mInsc and LGN/NuMA complex structures suggest distinct functions in asymmetric cell division for the Par3/mInsc/LGN and Gαi/LGN/NuMA pathways
Asymmetric cell division requires the establishment of cortical cell polarity and the
orientation of the mitotic spindle along the axis of cell polarity. Evidence from invertebrates …
orientation of the mitotic spindle along the axis of cell polarity. Evidence from invertebrates …
The human oral microbiome
The human oral cavity contains a number of different habitats, including the teeth, gingival
sulcus, tongue, cheeks, hard and soft palates, and tonsils, which are colonized by bacteria. …
sulcus, tongue, cheeks, hard and soft palates, and tonsils, which are colonized by bacteria. …
GetOrganelle: a fast and versatile toolkit for accurate de novo assembly of organelle genomes
GetOrganelle is a state-of-the-art toolkit to accurately assemble organelle genomes from
whole genome sequencing data. It recruits organelle-associated reads using a modified “…
whole genome sequencing data. It recruits organelle-associated reads using a modified “…
Initiation of atrial fibrillation by ectopic beats originating from the pulmonary veins: electrophysiological characteristics, pharmacological responses, and effects of …
…, MH Hsieh, CT Tai, CF Tsai, VS Prakash, WC Yu… - Circulation, 1999 - ahajournals.org
Background—Atrial fibrillation (AF) can be initiated by ectopic beats originating from the
atrial or great venous tissues. This study investigated the anatomic characteristics and …
atrial or great venous tissues. This study investigated the anatomic characteristics and …
[HTML][HTML] The Human Oral Microbiome Database: a web accessible resource for investigating oral microbe taxonomic and genomic information
The human oral microbiome is the most studied human microflora, but 53% of the species
have not yet been validly named and 35% remain uncultivated. The uncultivated taxa are …
have not yet been validly named and 35% remain uncultivated. The uncultivated taxa are …
A programmable diffractive deep neural network based on a digital-coding metasurface array
The development of artificial intelligence is typically focused on computer algorithms and
integrated circuits. Recently, all-optical diffractive deep neural networks have been created that …
integrated circuits. Recently, all-optical diffractive deep neural networks have been created that …
Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencing
…, A Danchin, I Saint Girons, RL Somerville, YM Wen… - Nature, 2003 - nature.com
Leptospirosis is a widely spread disease of global concern. Infection causes flu-like episodes
with frequent severe renal and hepatic damage, such as haemorrhage and jaundice. In …
with frequent severe renal and hepatic damage, such as haemorrhage and jaundice. In …