User profiles for Xuan Yuan

Yuan Xuan

MS Student in Information Systems, Cornell University
Verified email at cornell.edu
Cited by 273

A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability

…, S Thompson, MA Millrod, S Weinberg, X Yuan… - PloS one, 2011 - journals.plos.org
Background The production of cardiomyocytes from human induced pluripotent stem cells (hiPSC)
holds great promise for patient-specific cardiotoxicity drug testing, disease modeling, …

Effectiveness of exome and genome sequencing guided by acuity of illness for diagnosis of neurodevelopmental disorders

…, A Modrcin, S Herd, M Creed, Z Ye, X Yuan… - Science translational …, 2014 - science.org
Neurodevelopmental disorders (NDDs) affect more than 3% of children and are attributable
to single-gene mutations at more than 1000 loci. Traditional methods yield molecular …

Activin A maintains self-renewal and regulates fibroblast growth factor, Wnt, and bone morphogenic protein pathways in human embryonic stem cells

L Xiao, X Yuan, SJ Sharkis - Stem cells, 2006 - academic.oup.com
Human embryonic stem cells (hESCs) self-renew indefinitely while maintaining pluripotency.
The molecular mechanism underlying hESCs self-renewal and pluripotency is poorly …

Direct activation of the alternative complement pathway by SARS-CoV-2 spike proteins is blocked by factor D inhibition

J Yu, X Yuan, H Chen, S Chaturvedi… - Blood, The Journal …, 2020 - ashpublications.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly contagious
respiratory virus that can lead to venous/arterial thrombosis, stroke, renal failure, myocardial …

Functional role of oligomerization for bacterial and plant SWEET sugar transporter family

YH Xuan, YB Hu, LQ Chen, D Sosso, DC Ducat… - Proceedings of the …, 2013 - pnas.org
Eukaryotic sugar transporters of the MFS and SWEET superfamilies consist of 12 and 7 α-helical
transmembrane domains (TMs), respectively. Structural analyses indicate that MFS …

Neoadjuvant pembrolizumab in localized microsatellite instability high/deficient mismatch repair solid tumors

…, A Dasari, S Shin, A Hernandez, X Yuan… - Journal of Clinical …, 2023 - ascopubs.org
PURPOSE Pembrolizumab significantly improves clinical outcomes in advanced/metastatic
microsatellite instability high (MSI-H)/deficient mismatch repair (dMMR) solid tumors but is …

Formation and distribution of volcanic hydrocarbon reservoirs in sedimentary basins of China

…, CZ Jia, RK Zhu, GY Zhang, Z Xia, XJ Yuan - Petroleum Exploration …, 2008 - Elsevier
Volcanic hydrocarbon exploration in China has experienced three phases: accidental
discovery, local prospecting, and all-round exploration. There are mainly Carboniferous-Permian, …

High-glucose inhibits human fibroblast cell migration in wound healing via repression of bFGF-regulating JNK phosphorylation

YH Xuan, BB Huang, HS Tian, LS Chi, YM Duan… - PloS one, 2014 - journals.plos.org
One of the major symptoms of diabetes mellitus (DM) is delayed wound healing, which affects
large populations of patients worldwide. However, the underlying mechanism behind this …

Unbiased offline recommender evaluation for missing-not-at-random implicit feedback

L Yang, Y Cui, Y Xuan, C Wang, S Belongie… - Proceedings of the 12th …, 2018 - dl.acm.org
Implicit-feedback Recommenders (ImplicitRec) leverage positive only user-item interactions,
such as clicks, to learn personalized user preferences. Recommenders are often evaluated …

Rice Indeterminate 1 (OsId1) is necessary for the expression of Ehd1 (Early heading date 1) regardless of photoperiod

…, SH Park, CM Kim, CH Ryu, SH Park, Y Xuan… - The Plant …, 2008 - Wiley Online Library
Indeterminate 1 (Id1), a classical flowering gene first reported in 1946, is one of the earliest
genes whose expression in leaf tissues affects the floral transition in the shoot meristem. How …