Bioactive nanomotor enabling efficient intestinal barrier penetration for colorectal cancer therapy

ZH Wang, X Zeng, W Huang, Y Yang, S Zhang… - Nature …, 2025 - nature.com
Oral drug delivery systems had natural potential for colorectal cancer drug therapy. While the
drug delivery efficiency is severely hindered by the complex intestinal barriers, especially …

Seaweed-7b: Cost-effective training of video generation foundation model

…, H Chen, L Qi, S Wang, F Cheng, F Zuo, X Zeng… - arXiv preprint arXiv …, 2025 - arxiv.org
This technical report presents a cost-efficient strategy for training a video generation foundation
model. We present a mid-sized research model with approximately 7 billion parameters (…

Recent progress of micro/nanomotors to overcome physiological barriers in the gastrointestinal tract

…, C Zhu, W Huang, H Liu, M Yang, X Zeng… - Journal of Controlled …, 2023 - Elsevier
Oral administration is a convenient administration route for gastrointestinal disease therapy
with good patient compliance. But the nonspecific distribution of the oral drugs may cause …

Air pollution is associated with the development of atherosclerosis via the cooperation of CD36 and NLRP3 inflammasome in ApoE-/-mice

X Du, S Jiang, X Zeng, J Zhang, K Pan, J Zhou, Y Xie… - Toxicology Letters, 2018 - Elsevier
Previous studies have indicated that the main air pollutant fine particulate matter (≤2.5 μm;
PM 2.5 ) exposure is associated with the development of atherosclerosis. Although the …

Acoustic-Magnetic responsive nanomotor augments oral drug delivery by Gastrointestinal site navigation and mucus layer penetration

ZH Wang, X Zeng, S Zhang, H Li, J Zhou, Y Yang… - ACS …, 2025 - ACS Publications
Oral administration is a traditional, safe, and widely used drug delivery strategy. However,
the delivery efficiency of the oral drug delivery system is hindered by the long gastrointestinal …

Light-driven micro/nanomotors in biomedical applications

X Zeng, M Yang, H Liu, Z Zhang, Y Hu, J Shi, ZH Wang - Nanoscale, 2023 - pubs.rsc.org
Nanotechnology brings hope for targeted drug delivery. However, most current drug delivery
systems use passive delivery strategies with limited therapeutic efficiency. Over the past …

Seedance 1.0: Exploring the boundaries of video generation models

…, R Yang, T Yang, Y Yang, Z Ye, X Zeng, Y Zeng… - arXiv preprint arXiv …, 2025 - arxiv.org
Notable breakthroughs in diffusion modeling have propelled rapid improvements in video
generation, yet current foundational model still face critical challenges in simultaneously …

Fine particulate matter-induced cardiovascular injury is associated with NLRP3 inflammasome activation in Apo E-/-mice

X Du, S Jiang, X Zeng, J Zhang, K Pan, L Song… - Ecotoxicology and …, 2019 - Elsevier
Epidemiological evidences have indicated that fine particulate matter (PM 2.5 ) is associated
with the increased risk of cardiovascular morbidity and mortality. Although several …

Combined effects of vitamin E and omega-3 fatty acids on protecting ambient PM2. 5-induced cardiovascular injury in rats

X Du, S Jiang, L Bo, J Liu, X Zeng, Y Xie, Q He, X Ye… - Chemosphere, 2017 - Elsevier
Objective This study aims to observe whether the combined treatment with vitamin E (vit E)
and omega-3 polyunsaturated fatty acids (Ω-3 FA) could prevent the fine particulate matter (…

AMPK activation attenuates inflammatory response to reduce ambient PM2. 5-induced metabolic disorders in healthy and diabetic mice

K Pan, S Jiang, X Du, X Zeng, J Zhang, L Song… - Ecotoxicology and …, 2019 - Elsevier
Epidemiological and experimental studies have indicated that ambient fine particulate
matter (PM 2.5 ) exposure is associated with the occurrence and development of metabolic …