Glycogen-based pH and redox sensitive nanoparticles with ginsenoside Rh2 for effective treatment of ulcerative colitis

Y Xu, BW Zhu, X Li, YF Li, XM Ye, JN Hu - Biomaterials, 2022 - Elsevier
The purpose of this study is to construct a pH and redox sensitive nanoparticle to effectively
deliver ginsenoside Rh 2 for the treatment of ulcerative colitis (UC). Herein, glycogen was …

Investigation of chemical composition, antioxidant activity, and the effects of alfalfa flavonoids on growth performance

…, X Li, X Liu, N Wang, Q An, XM Ye… - Oxidative medicine …, 2020 - Wiley Online Library
The flavonoids were extracted from alfalfa using ethanol assisted with ultrasonic extraction
and purified by D101 macroporous resin column chromatography. The chemical composition …

Chemical Composition and Antioxidant Activities of Polysaccharides from Yingshan Cloud Mist Tea

…, JE Li, N Wang, X Liu, Q An, XM Ye… - Oxidative medicine …, 2019 - Wiley Online Library
The study was designed to investigate the chemical composition and antioxidant activities
of polysaccharides from Yingshan Cloud Mist Tea. The chemical composition of green tea …

Effects of polysaccharides from Yingshan Yunwu tea on meat quality, immune status and intestinal microflora in chickens

ZT Zhao, XM Ye, KH Ouyang, WJ Wang - International Journal of …, 2020 - Elsevier
The present study was aimed to investigate the effects of the addition of Yingshan Yunwu
green tea polysaccharide conjugates (GTPC) on meat quality, immune response and gut …

Circuit QED: generation of two-transmon-qutrit entangled states via resonant interaction

XM Ye, ZF Zheng, DM Lu, CP Yang - Quantum Information Processing, 2018 - Springer
We present a way to create entangled states of two superconducting transmon qutrits based
on circuit QED. Here, a qutrit refers to a three-level quantum system. Since only resonant …

3-Aroylmethylene-2,3,6,7-tetrahydro-1H-pyrazino[2,1-a]isoquinolin-4(11bH)-ones as Potent Nrf2/ARE Inducers in Human Cancer Cells and AOM-DSS Treated Mice

…, J Zhu, L Xu, Z Jiang, X Xue, M Ye… - Journal of Medicinal …, 2013 - ACS Publications
Nrf2-mediated activation of ARE regulates expression of cytoprotective enzymes against
oxidative stress, inflammation, and carcinogenesis. We have discovered a novel structure (1) as …

Large-scale pollen distribution in marine surface sediments from the Bohai Sea, China: Insights into pollen provenance, transport, deposition, and coastal-shelf …

S Yang, B Song, S Ye, EA Laws, L He, J Li… - Progress in …, 2019 - Elsevier
To elucidate the mechanisms responsible for pollen and spore transportation and deposition
in the Bohai Sea, fully covered seafloor-surface sediment samples were collected for …

Synthesis and bioevaluation of a series of α-pyrone derivatives as potent activators of Nrf2/ARE pathway (part I)

M Xi, Z Sun, H Sun, J Jia, Z Jiang, L Tao, M Ye… - European journal of …, 2013 - Elsevier
When exposed to electrophiles, human colorectal cancer cells (HCT116) counteract oxidative
stress through activating NF-E2-related factor 2 (Nrf2)/antioxidant response element (ARE) …

Discovery and modification of in vivo active Nrf2 activators with 1, 2, 4-oxadiazole core: hits identification and structure–activity relationship study

LL Xu, JF Zhu, XL Xu, J Zhu, L Li, MY Xi… - Journal of medicinal …, 2015 - ACS Publications
Induction of phase II antioxidant enzymes by activation of Nrf2/ARE pathway has been
recognized as a promising strategy for the regulation of oxidative stress-related diseases. Herein …

Hypoglycemic mechanisms of Polygonatum sibiricum polysaccharide in db/db mice via regulation of glycolysis/gluconeogenesis pathway and alteration of gut …

X Chen, Y Tong, Z Ren, S Chen, X Mei, Q Zhou, G Dai - Heliyon, 2023 - cell.com
Polygonatum rhizoma polysaccharide (PP) is a main ingredient of Polygonatum rhizoma,
which is both food and traditional herbal medicine. In this study, we aimed to investigate the …