The adult mammalian heart possesses little regenerative potential following injury. Fibrosis
due to activation of cardiac fibroblasts impedes cardiac regeneration and contributes to loss …

MicroRNAs (miRNAs) interfere with translation of specific target mRNAs and are thought to
thereby regulate many cellular processes. Recent studies have suggested that miRNAs might …

Phospholipids have the characteristics of excellent biocompatibility and a especial
amphiphilicity. These unique properties make phospholipids most appropriate to be employed as …

Ganoderma lucidum is a widely used medicinal macrofungus in traditional Chinese medicine
that creates a diverse set of bioactive compounds. Here we report its 43.3-Mb genome, …

The presence of duplicates introduced by PCR amplification is a major issue in paired short
reads from next-generation sequencing platforms. These duplicates might have a serious …

Heart failure with preserved ejection fraction (HFpEF) is a common syndrome with high
morbidity and mortality for which there are no evidence-based therapies. Here we report that …

Reprogramming of mouse fibroblasts toward a myocardial cell fate by forced expression of
cardiac transcription factors or microRNAs has recently been demonstrated. The potential …

Systemically administered tumor-targeted Salmonella has been developed as an anticancer
agent, although its use could be limited by the potential induction of tumor necrosis factor α (…

Bone marrow mesenchymal stem cells (BMSCs) exhibit an age-dependent reduction in
osteogenesis that is accompanied by an increased propensity toward adipocyte differentiation. …

Our study indicates that recombinant adiponectin induced RANKL and inhibited OPG expression
in human osteoblasts through the AdipoR1/p38 MAPK pathway, and these responses …