User profiles for Xiaohong Yu

Xiao-Hong Yu

Researcher, Stony Brook University & Brookhaven National Laboratory
Verified email at bnl.gov
Cited by 2499

Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)

…, MA McDonough, ML Coleman, CH Coles, X Yu… - Proceedings of the …, 2006 - pnas.org
Studies on hypoxia-sensitive pathways have revealed a series of Fe(II)-dependent dioxygenases
that regulate hypoxia-inducible factor (HIF) by prolyl and asparaginyl hydroxylation. …

T-cell-replete haploidentical HSCT with low-dose anti-T-lymphocyte globulin compared with matched sibling HSCT and unrelated HSCT

…, W Xie, W Zheng, Y Zhu, X Ye, X Yu… - Blood, The Journal …, 2014 - ashpublications.org
We developed an approach of T-cell-replete haploidentical hematopoietic stem cell
transplantation (HSCT) with low-dose anti-T-lymphocyte globulin and prospectively compared …

Characterization of the ATPase activity of P-glycoprotein from multidrug-resistant Chinese hamster ovary cells

FJ Sharom, X Yu, JWK Chu, CA Doige - Biochemical Journal, 1995 - portlandpress.com
P-Glycoprotein (Pgp) was isolated from CHRC5 membranes by selective detergent extraction
and further purified by lentil lectin affinity chromatography. The purified product displayed …

Titanium dioxide nanoparticle-induced testicular damage, spermatogenesis suppression, and gene expression alterations in male mice

…, X Ze, S Gui, L Sheng, Q Sun, J Hong, X Yu… - Journal of hazardous …, 2013 - Elsevier
Although titanium dioxide nanoparticles (TiO 2 NPs) have been demonstrated to
accumulate in organs resulting in toxicity, there is currently only limited data regarding male …

[HTML][HTML] Functional reconstitution of drug transport and ATPase activity in proteoliposomes containing partially purified P-glycoprotein.

FJ Sharom, X Yu, CA Doige - Journal of Biological Chemistry, 1993 - Elsevier
P-glycoprotein, the multidrug transporter, is proposed to act as an ATP-driven drug efflux
pump. We previously reported the partial purification of P-glycoprotein from multidrug-resistant …

TiO2 Nanoparticles Induced Hippocampal Neuroinflammation in Mice

Y Ze, L Sheng, X Zhao, J Hong, X Ze, X Yu, X Pan… - PloS one, 2014 - journals.plos.org
Titanium dioxide nanoparticles (TiO 2 NPs) have been used in various medical and industrial
areas. However, the impacts of these nanoparticles on neuroinflammation in the brain are …

The effects of lipids and detergents on ATPase-active P-glycoprotein

CA Doige, X Yu, FJ Sharom - Biochimica et Biophysica Acta (BBA) …, 1993 - Elsevier
We previously isolated and characterized a partially purified preparation of ATPase-active P-glycoprotein,
the multidrug transporter (Doige, CA, Yu, X. and Sharon, FJ (1992) Biochim. …

[HTML][HTML] In-situ anchoring of Fe3O4/ZIF-67 dodecahedrons in highly compressible wood aerogel with excellent microwave absorption properties

L Xu, Y Xiong, B Dang, Z Ye, C Jin, Q Sun, X Yu - Materials & Design, 2019 - Elsevier
Lightweight aerogels with superior cavities have attracted great interest in the field of
electromagnetic wave absorbing materials. In this work, a hierarchical porous wood aerogel …

Increased accumulation of the cardio-cerebrovascular disease treatment drug tanshinone in Salvia miltiorrhiza hairy roots by the enzymes 3-hydroxy-3-methylglutaryl CoA …

M Shi, X Luo, G Ju, X Yu, X Hao, Q Huang… - Functional & integrative …, 2014 - Springer
Tanshinone is widely used for treatment of cardio-cerebrovascular diseases with increasing
demand. Herein, key enzyme genes SmHMGR (3-hydroxy-3-methylglutaryl CoA reductase) …

Progress of in vivo studies on the systemic toxicities induced by titanium dioxide nanoparticles

F Hong, X Yu, N Wu, YQ Zhang - Toxicology research, 2017 - academic.oup.com
Titanium dioxide nanoparticles (TiO 2 NPs) are inorganic materials with a diameter of 1–100
nm. In recent years, TiO 2 NPs have been used in a wide range of products, including food, …