Genome-wide association study dissects the genetic architecture of oil biosynthesis in maize kernels

H Li, Z Peng, X Yang, W Wang, J Fu, J Wang, Y Han… - Nature …, 2013 - nature.com
Maize kernel oil is a valuable source of nutrition. Here we extensively examine the genetic
architecture of maize oil biosynthesis in a genome-wide association study using 1.03 million …

Associations of breast cancer risk factors with tumor subtypes: a pooled analysis from the Breast Cancer Association Consortium studies

XR Yang, J Chang-Claude, EL Goode… - Journal of the …, 2011 - academic.oup.com
Background Previous studies have suggested that breast cancer risk factors are associated
with estrogen receptor (ER) and progesterone receptor (PR) expression status of the tumors. …

Convergent selection of a WD40 protein that enhances grain yield in maize and rice

W Chen, L Chen, X Zhang, N Yang, J Guo, M Wang… - Science, 2022 - science.org
A better understanding of the extent of convergent selection among crops could greatly improve
breeding programs. We found that the quantitative trait locus KRN2 in maize and its rice …

Interactions between Sox9 and β-catenin control chondrocyte differentiation

…, JP Lyons, Y Mori-Akiyama, X Yang… - Genes & …, 2004 - genesdev.cshlp.org
Chondrogenesis is a multistep process that is essential for endochondral bone formation.
Previous results have indicated a role for β-catenin and Wnt signaling in this pathway. Here we …

Differences in risk factors for breast cancer molecular subtypes in a population-based study

XR Yang, ME Sherman, DL Rimm, J Lissowska… - … Biomarkers & Prevention, 2007 - AACR
Abstract Analysis of gene expression data suggests that breast cancers are divisible into
molecular subtypes which have distinct clinical features. This study evaluates whether …

Deep-learning-enabled protein–protein interaction analysis for prediction of SARS-CoV-2 infectivity and variant evolution

…, K Wang, Y Gao, G Li, DT Baptista-Hon, XH Yang… - Nature Medicine, 2023 - nature.com
Host–pathogen interactions and pathogen evolution are underpinned by protein–protein
interactions between viral and host proteins. An understanding of how viral variants affect …

Rare genetic variation at Zea mays crtRB1 increases β-carotene in maize grain

…, CB Kandianis, CE Harjes, L Bai, EH Kim, X Yang… - Nature …, 2010 - nature.com
Breeding to increase β-carotene levels in cereal grains, termed provitamin A biofortification,
is an economical approach to address dietary vitamin A deficiency in the developing world. …

Genetic variation in ZmVPP1 contributes to drought tolerance in maize seedlings

X Wang, H Wang, S Liu, A Ferjani, J Li, J Yan, X Yang… - Nature …, 2016 - nature.com
Maize production is threatened by drought stress worldwide. Identification of the genetic
components underlying drought tolerance in maize is of great importance. Here we report a …

A transposable element in a NAC gene is associated with drought tolerance in maize seedlings

H Mao, H Wang, S Liu, Z Li, X Yang, J Yan, J Li… - Nature …, 2015 - nature.com
Drought represents a major constraint on maize production worldwide. Understanding the
genetic basis for natural variation in drought tolerance of maize may facilitate efforts to …

The protein product of the tumor suppressor gene, melanoma differentiation-associated gene 7, exhibits immunostimulatory activity and is designated IL-24

…, S Ekmekcioglu, AM Mhashilkar, XH Yang… - The Journal of …, 2002 - journals.aai.org
The melanoma differentiation-associated gene 7 (mda-7) has been studied primarily in the
context of its tumor suppressor activity. Although mda-7 has been designated as IL-24 based …