User profiles for Xing Liu

xing liu

University of science and technology of China
Verified email at email.ncu.edu.cn
Cited by 747

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

X Liu, Z Zhang, J Ruan, Y Pan, VG Magupalli, H Wu… - Nature, 2016 - nature.com
Inflammatory caspases (caspases 1, 4, 5 and 11) are activated in response to microbial
infection and danger signals. When activated, they cleave mouse and human gasdermin D (…

Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China

D Wang, B Hu, C Hu, F Zhu, X Liu, J Zhang, B Wang… - jama, 2020 - jamanetwork.com
Importance In December 2019, novel coronavirus (2019-nCoV)–infected pneumonia (NCIP)
occurred in Wuhan, China. The number of cases has increased rapidly but information on …

Fine pore engineering in a series of isoreticular metal-organic frameworks for efficient C2H2/CO2 separation

J Wang, Y Zhang, Y Su, X Liu, P Zhang, RB Lin… - Nature …, 2022 - nature.com
The separation of C 2 H 2 /CO 2 is not only industrially important for acetylene purification
but also scientifically challenging owing to their high similarities in physical properties and …

Gasdermin E suppresses tumour growth by activating anti-tumour immunity

Z Zhang, Y Zhang, S Xia, Q Kong, S Li, X Liu… - Nature, 2020 - nature.com
Cleavage of the gasdermin proteins to produce pore-forming amino-terminal fragments causes
inflammatory cell death (pyroptosis) 1 . Gasdermin E (GSDME, also known as DFNA5)—…

[HTML][HTML] Prominent changes in blood coagulation of patients with SARS-CoV-2 infection

…, L Yang, R Liu, F Liu, K Wu, J Li, X Liu… - Clinical Chemistry and …, 2020 - degruyter.com
Background As the number of patients increases, there is a growing understanding of the form
of pneumonia sustained by the 2019 novel coronavirus (SARS-CoV-2), which has caused …

Channelling inflammation: gasdermins in physiology and disease

X Liu, S Xia, Z Zhang, H Wu, J Lieberman - Nature reviews Drug …, 2021 - nature.com
Gasdermins were recently identified as the mediators of pyroptosis — inflammatory cell death
triggered by cytosolic sensing of invasive infection and danger signals. Upon activation, …

Streptococcal pyrogenic exotoxin B cleaves GSDMA and triggers pyroptosis

…, W Li, R Miao, Z Zhang, TS Kupper, J Lieberman, X Liu - Nature, 2022 - nature.com
Gasdermins, a family of five pore-forming proteins (GSDMA–GSDME) in humans expressed
predominantly in the skin, mucosa and immune sentinel cells, are key executioners of …

Fungal diversity notes 111–252—taxonomic and phylogenetic contributions to fungal taxa

…, I Kytövuori, JD Lawrey, J Xing, H Li, ZY Liu, XZ Liu… - Fungal diversity, 2015 - Springer
This paper is a compilation of notes on 142 fungal taxa, including five new families, 20 new
genera, and 100 new species, representing a wide taxonomic and geographic range. The …

Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis

…, H Wu, JC Kagan, RN Kitsis, P Zhang, X Liu… - Immunity, 2023 - cell.com
Gasdermin D (GSDMD)-activated inflammatory cell death (pyroptosis) causes mitochondrial
damage, but its underlying mechanism and functional consequences are largely unknown. …

[HTML][HTML] Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays

…, X Liu, X Huang, Z Li, Y Hong, Y Jiang, J Peng, S Liu… - Cell, 2022 - cell.com
Spatially resolved transcriptomic technologies are promising tools to study complex
biological processes such as mammalian embryogenesis. However, the imbalance between …