Targeted delivery of therapeutic nanoparticles in a disease-specific manner represents a
potentially powerful technology especially when treating infiltrative brain tumors such as …

In this study, a dual-targeting drug delivery system based on PEGylated oxidized multi-walled
carbon nanotubes (O-MWNTs) modified with angiopep-2 (O-MWNTs-PEG-ANG) was …

Mesoporous silica-encapsulated gold nanorods (GNRs@mSiO 2 ) have great potential both
in photothermal therapy and drug delivery. In this paper, we firstly developed GNRs@mSiO …

The lactoferrin (Lf) conjugated poly (ethyleneglycol)–poly (lactide) nanoparticle (Lf–NP) was
constructed in this paper as a novel biodegradable brain drug delivery system with …

Pulmonary hypertension (PH) is a serious condition that affects mainly young and middle-aged
women, and its etiology is poorly understood. A prominent pathological feature of PH is …

The purpose of this study was to improve the solubility and enhance the brain uptake of
nimodipine (NM) in an o/w microemulsion, which was suitable for intranasal delivery. Three …

In order to improve the absorption of nanoparticles in the brain following nasal administration,
a novel protocol to conjugate biorecognitive ligands—lectins to the surface of poly (…

Nanoparticles (NPs) were widely used in drugs/probes delivery for improved disease
diagnosis and/or treatment. Targeted delivery to cancer cells is a highly attractive application of …

Transports of methotrexate-loaded polybutylcyanoacrylate nanoparticles with different sizes
across blood brain barrier were investigated in this experiment. The drug-loaded …

The relative impermeability of the blood-brain barrier (BBB) results from tight junctions and
efflux transport systems limits drug delivery to the central nervous system (CNS), and thus …