Comparative genetic architectures of schizophrenia in East Asian and European populations

M Lam, CY Chen, Z Li, AR Martin, J Bryois, X Ma… - Nature …, 2019 - nature.com
Schizophrenia is a debilitating psychiatric disorder with approximately 1% lifetime risk globally.
Large-scale schizophrenia genetic studies have reported primarily on European ancestry …

Genetic origins and sex-biased admixture of the Huis

X Ma, W Yang, Y Gao, Y Pan, Y Lu… - Molecular Biology …, 2021 - academic.oup.com
The Hui people are unique among Chinese ethnic minorities in that they speak the same
language as Han Chinese (HAN) but practice Islam. However, as the second-largest minority …

Archaic introgression contributed to the pre-agriculture adaptation of vitamin B1 metabolism in East Asia

X Ma, S Xu - IScience, 2022 - cell.com
Thiamine (vitamin B1) is an essential micronutrient. Genes involved in thiamine metabolisms,
such as SLC19A2, SLC35F3, and SLC35F4, were assumed to be underlying positive …

Neanderthal adaptive introgression shaped LCT enhancer region diversity without linking to lactase persistence in East Asian populations

X Ma, Y Lu, M Stoneking, S Xu - Proceedings of the National Academy of …, 2025 - pnas.org
Positive selection at the 2q21.3 enhancer region for lactase gene (LCT) expression in
Europeans and Africans has long been attributed to selection for lactase persistence (LP), the …

PGG.Han: the Han Chinese genome database and analysis platform

…, X Wang, C Liu, Y Pan, X Zhang, X Ma… - Nucleic Acids …, 2020 - academic.oup.com
As the largest ethnic group in the world, the Han Chinese population is nonetheless
underrepresented in global efforts to catalogue the genomic variability of natural populations. Here, …

Refining models of archaic admixture in Eurasia with ArchaicSeeker 2.0

…, L Deng, R Zhang, Y Gao, X Ge, J Liu, X Ma… - Nature …, 2021 - nature.com
We developed a method, ArchaicSeeker 2.0, to identify introgressed hominin sequences
and model multiple-wave admixture. The new method enabled us to discern two waves of …

Adaptive evolution of two distinct adaptive haplotypes of Neanderthal origin at the immunoglobulin heavy-chain locus in East Asian and European populations

X Ma, Y Lu, S Xu - Molecular Biology and Evolution, 2024 - academic.oup.com
Immunoglobulins (Igs) have a crucial role in humoral immunity. Two recent studies have
reported a high-frequency Neanderthal-introgressed haplotype throughout Eurasia and a high-…

[PDF][PDF] Genetic origins and adaptive evolution of the Deng people on the Tibetan Plateau

…, S Chen, Y Gao, L Ma, L Liu, J Liu, X Ma… - Molecular Biology …, 2023 - academic.oup.com
The Tibetan Plateau is populated by diverse ethnic groups, but most of them are underrepresented
in genomics studies compared with the Tibetans (TIB). Here, to gain further insight …

Ancestral origins and admixture history of Kazakhs

…, R Zhang, Y Pan, Y Lu, Y Gao, X Ma… - Molecular Biology …, 2024 - academic.oup.com
Kazakh people, like many other populations that settled in Central Asia, demonstrate an
array of mixed anthropological features of East Eurasian (EEA) and West Eurasian (WEA) …

Wet dispersion of graphene assisted constructing multiple interface pores of PVDF hollow fiber membranes via melt-spinning and stretching

D Ji, W Lin, G Sun, X Tian, X Ma, C Xiao - Journal of Environmental …, 2023 - Elsevier
In this work, in order to further improve the permeability of poly(vinylidene fluoride) (PVDF)
hollow fiber microfiltration membranes through melt-spinning and stretching (MS-S), we …