Comparative genetic architectures of schizophrenia in East Asian and European populations
Schizophrenia is a debilitating psychiatric disorder with approximately 1% lifetime risk globally.
Large-scale schizophrenia genetic studies have reported primarily on European ancestry …
Large-scale schizophrenia genetic studies have reported primarily on European ancestry …
Genetic origins and sex-biased admixture of the Huis
X Ma, W Yang, Y Gao, Y Pan, Y Lu… - Molecular Biology …, 2021 - academic.oup.com
The Hui people are unique among Chinese ethnic minorities in that they speak the same
language as Han Chinese (HAN) but practice Islam. However, as the second-largest minority …
language as Han Chinese (HAN) but practice Islam. However, as the second-largest minority …
Archaic introgression contributed to the pre-agriculture adaptation of vitamin B1 metabolism in East Asia
X Ma, S Xu - IScience, 2022 - cell.com
Thiamine (vitamin B1) is an essential micronutrient. Genes involved in thiamine metabolisms,
such as SLC19A2, SLC35F3, and SLC35F4, were assumed to be underlying positive …
such as SLC19A2, SLC35F3, and SLC35F4, were assumed to be underlying positive …
Neanderthal adaptive introgression shaped LCT enhancer region diversity without linking to lactase persistence in East Asian populations
X Ma, Y Lu, M Stoneking, S Xu - Proceedings of the National Academy of …, 2025 - pnas.org
Positive selection at the 2q21.3 enhancer region for lactase gene (LCT) expression in
Europeans and Africans has long been attributed to selection for lactase persistence (LP), the …
Europeans and Africans has long been attributed to selection for lactase persistence (LP), the …
PGG.Han: the Han Chinese genome database and analysis platform
As the largest ethnic group in the world, the Han Chinese population is nonetheless
underrepresented in global efforts to catalogue the genomic variability of natural populations. Here, …
underrepresented in global efforts to catalogue the genomic variability of natural populations. Here, …
Refining models of archaic admixture in Eurasia with ArchaicSeeker 2.0
We developed a method, ArchaicSeeker 2.0, to identify introgressed hominin sequences
and model multiple-wave admixture. The new method enabled us to discern two waves of …
and model multiple-wave admixture. The new method enabled us to discern two waves of …
Adaptive evolution of two distinct adaptive haplotypes of Neanderthal origin at the immunoglobulin heavy-chain locus in East Asian and European populations
X Ma, Y Lu, S Xu - Molecular Biology and Evolution, 2024 - academic.oup.com
Immunoglobulins (Igs) have a crucial role in humoral immunity. Two recent studies have
reported a high-frequency Neanderthal-introgressed haplotype throughout Eurasia and a high-…
reported a high-frequency Neanderthal-introgressed haplotype throughout Eurasia and a high-…
[PDF][PDF] Genetic origins and adaptive evolution of the Deng people on the Tibetan Plateau
…, S Chen, Y Gao, L Ma, L Liu, J Liu, X Ma… - Molecular Biology …, 2023 - academic.oup.com
The Tibetan Plateau is populated by diverse ethnic groups, but most of them are underrepresented
in genomics studies compared with the Tibetans (TIB). Here, to gain further insight …
in genomics studies compared with the Tibetans (TIB). Here, to gain further insight …
Ancestral origins and admixture history of Kazakhs
Kazakh people, like many other populations that settled in Central Asia, demonstrate an
array of mixed anthropological features of East Eurasian (EEA) and West Eurasian (WEA) …
array of mixed anthropological features of East Eurasian (EEA) and West Eurasian (WEA) …
Wet dispersion of graphene assisted constructing multiple interface pores of PVDF hollow fiber membranes via melt-spinning and stretching
D Ji, W Lin, G Sun, X Tian, X Ma, C Xiao - Journal of Environmental …, 2023 - Elsevier
In this work, in order to further improve the permeability of poly(vinylidene fluoride) (PVDF)
hollow fiber microfiltration membranes through melt-spinning and stretching (MS-S), we …
hollow fiber microfiltration membranes through melt-spinning and stretching (MS-S), we …