Emergence of SARS-CoV-2 through recombination and strong purifying selection
COVID-19 has become a global pandemic caused by the novel coronavirus SARS-CoV-2.
Understanding the origins of SARS-CoV-2 is critical for deterring future zoonosis, discovering …
Understanding the origins of SARS-CoV-2 is critical for deterring future zoonosis, discovering …
COVID-19 transmission in Mainland China is associated with temperature and humidity: A time-series analysis
COVID-19 has become a pandemic. The influence of meteorological factors on the transmission
and spread of COVID-19 is of interest. This study sought to examine the associations of …
and spread of COVID-19 is of interest. This study sought to examine the associations of …
Harvesting waste heat with flexible Bi2Te3 thermoelectric thin film
Thermoelectric materials offer the possibility of harvesting huge amounts of waste heat, such
as vehicle exhaust gases, and converting them directly into useful electricity, a process that …
as vehicle exhaust gases, and converting them directly into useful electricity, a process that …
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells
…, L Silverman, A Miller, F Wang, H Yang, Y Chen… - Science, 2013 - science.org
The recent discovery of mutations in metabolic enzymes has rekindled interest in harnessing
the altered metabolism of cancer cells for cancer therapy. One potential drug target is …
the altered metabolism of cancer cells for cancer therapy. One potential drug target is …
3D charge and 2D phonon transports leading to high out-of-plane ZT in n-type SnSe crystals
…, Y Pei, CF Wu, X Wu, H Yu, F Zhu, K Wang, Y Chen… - Science, 2018 - science.org
Thermoelectric technology enables the harvest of waste heat and its direct conversion into
electricity. The conversion efficiency is determined by the materials figure of merit ZT. Here we …
electricity. The conversion efficiency is determined by the materials figure of merit ZT. Here we …
[HTML][HTML] Acetylation is indispensable for p53 activation
The activation of the tumor suppressor p53 facilitates the cellular response to genotoxic stress;
however, the p53 response can only be executed if its interaction with its inhibitor Mdm2 …
however, the p53 response can only be executed if its interaction with its inhibitor Mdm2 …
Substrate and functional diversity of lysine acetylation revealed by a proteomics survey
Acetylation of proteins on lysine residues is a dynamic posttranslational modification that is
known to play a key role in regulating transcription and other DNA-dependent nuclear …
known to play a key role in regulating transcription and other DNA-dependent nuclear …
Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus
…, MK Louder, LM Tran, Y Chen, F Cai, S Chen… - Nature, 2013 - nature.com
Current human immunodeficiency virus-1 (HIV-1) vaccines elicit strain-specific neutralizing
antibodies. However, cross-reactive neutralizing antibodies arise in approximately 20% of …
antibodies. However, cross-reactive neutralizing antibodies arise in approximately 20% of …
JMJD6 is a histone arginine demethylase
Arginine methylation occurs on a number of proteins involved in a variety of cellular functions.
Histone tails are known to be mono- and dimethylated on multiple arginine residues …
Histone tails are known to be mono- and dimethylated on multiple arginine residues …
Myeloid-derived suppressor cells as immunosuppressive regulators and therapeutic targets in cancer
K Li, H Shi, B Zhang, X Ou, Q Ma, Y Chen… - Signal transduction and …, 2021 - nature.com
Myeloid-derived suppressor cells (MDSCs) are a heterogenic population of immature myeloid
cells with immunosuppressive effects, which undergo massive expansion during tumor …
cells with immunosuppressive effects, which undergo massive expansion during tumor …