Co–ferrocene MOF/glucose oxidase as cascade nanozyme for effective tumor therapy

C Fang, Z Deng, G Cao, Q Chu, Y Wu… - Advanced Functional …, 2020 - Wiley Online Library
Chemodynamic therapy (CDT), enabling selective therapeutic effects and low side effect,
attracts increasing attention in recent years. However, limited intracellular content of H 2 O 2 …

High operative risk of cool‐tip radiofrequency ablation for unresectable pancreatic head cancer

Y Wu, Z Tang, H Fang, S Gao, J Chen… - Journal of surgical …, 2006 - Wiley Online Library
Background and Objectives To report and discuss the effect, complications and mortality of
cool‐tip radiofrequency ablation (RFA) for unresectable pancreatic cancer. Methods During …

Dual enzymatic reaction-assisted gemcitabine delivery systems for programmed pancreatic cancer therapy

H Han, D Valdepérez, Q Jin, B Yang, Z Li, Y Wu… - Acs Nano, 2017 - ACS Publications
Dual enzymatic reactions were introduced to fabricate programmed gemcitabine (GEM)
nanovectors for targeted pancreatic cancer therapy. Dual-enzyme-sensitive GEM nanovectors …

Enzyme-triggered transcytosis of dendrimer–drug conjugate for deep penetration into pancreatic tumors

G Wang, Z Zhou, Z Zhao, Q Li, Y Wu, S Yan, Y Shen… - ACS …, 2020 - ACS Publications
The dense fibrotic stroma in pancreatic ductal adenocarcinoma (PDA) resists drug diffusion
into the tumor and leads to an unsatisfactory prognosis. To address this problem, we …

Anthocyanins from Chinese bayberry extract protect β cells from oxidative stress-mediated injury via HO-1 upregulation

…, Q Xie, B Xu, C Sun, K Chen, Y Wu - Journal of agricultural …, 2011 - ACS Publications
Oxidative stress plays a pivotal role during the islet transplantation procedure, and antioxidant
supplementation may protect grafts against oxidative injury. Chinese bayberry is one of …

Neoadjuvant therapy for patients with borderline resectable pancreatic cancer: a systematic review and meta-analysis of response and resection percentages

K Tang, W Lu, W Qin, Y Wu - Pancreatology, 2016 - Elsevier
Background We systematically reviewed and performed a meta-analysis of the available
data regarding neoadjuvant chemo- and/or radiotherapy with special emphasis on tumor …

Inhibition of autophagy promotes metastasis and glycolysis by inducing ROS in gastric cancer cells

…, M Kang, B Zhang, B Yang, B Li, H Yang, Y Wu - …, 2015 - pmc.ncbi.nlm.nih.gov
Autophagy defect has been shown to be correlated with malignant phenotype and poor
prognosis of human cancers, however, the detailed mechanisms remain obscure. In this study, …

O-GlcNAcylation and stablization of SIRT7 promote pancreatic cancer progression by blocking the SIRT7-REGγ interaction

…, L Zheng, J Lou, C Lin, J Gong, Y Zhu, Y Wu - Cell Death & …, 2022 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers and its dismal
prognosis indicates the urgent need to elucidate the potential oncogenic mechanisms. SIRT7 …

Exosomes derived from pancreatic cancer cells induce insulin resistance in C2C12 myotube cells through the PI3K/Akt/FoxO1 pathway

…, Q Chen, W Qin, C Li, Y Zhang, Y Shao, Y Wu - Scientific reports, 2017 - nature.com
Prospective epidemiological studies have consistently suggested that pancreatic cancer-associated
new-onset diabetes mellitus (PC-DM) represents a potential platform for early …

Elevated levels of plasma fibrinogen in patients with pancreatic cancer: possible role of a distant metastasis predictor

…, B Zhang, X Dong, Q Xie, E Guo, H Huang, Y Wu - Pancreas, 2009 - journals.lww.com
Objectives: Although changes of plasma fibrinogen have been documented in limited pancreatic
malignant tumors, a relationship between plasma fibrinogen and pancreatic cancer in a …