Online controlled experiments at large scale

R Kohavi, A Deng, B Frasca, T Walker, Y Xu… - Proceedings of the 19th …, 2013 - dl.acm.org
Web-facing companies, including Amazon, eBay, Etsy, Facebook, Google, Groupon, Intuit,
LinkedIn, Microsoft, Netflix, Shop Direct, StumbleUpon, Yahoo, and Zynga use online …

Geography-informed energy conservation for ad hoc routing

Y Xu, J Heidemann, D Estrin - … of the 7th annual international conference …, 2001 - dl.acm.org
We introduce a geographical adaptive fidelity (GAF) algorithm that reduces energy
consumption in ad hoc wireless networks. GAF conserves energy by identifying nodes that are …

Advances in network simulation

…, A Helmy, P Huang, S McCanne, K Varadhan, Y Xu… - Computer, 2000 - ieeexplore.ieee.org
Network researchers must test Internet protocols under varied conditions to determine whether
they are robust and reliable. The paper discusses the Virtual Inter Network Testbed (VINT…

Long noncoding RNAs: novel players in colorectal cancer

D Han, M Wang, N Ma, Y Xu, Y Jiang, X Gao - Cancer letters, 2015 - Elsevier
Colorectal cancer (CRC) is the most common type of cancer in the world. Despite its
commonness, the underlying mechanism of CRC is not completely understood. Long noncoding …

Surgical stress and cancer progression: the twisted tango

Z Chen, P Zhang, Y Xu, J Yan, Z Liu, WB Lau, B Lau… - Molecular cancer, 2019 - Springer
Surgical resection is an important avenue for cancer treatment, which, in most cases, can
effectively alleviate the patient symptoms. However, accumulating evidence has documented …

Non‐covalent functionalization of carbon nanotubes with surfactants and polymers

CY Hu, YJ Xu, SW Duo, RF Zhang… - Journal of the Chinese …, 2009 - Wiley Online Library
Carbon nanotubes (CNTs) possessing unique structure and properties are attractive
building blocks for novel materials and devices of important practical interest. However, the …

Structural determinants of the cellular localization and shuttling of TDP-43

YM Ayala, P Zago, A D'Ambrogio, YF Xu… - Journal of cell …, 2008 - journals.biologists.com
TDP-43 (also known as TARDBP) regulates different processes of gene expression, including
transcription and splicing, through RNA and DNA binding. Moreover, recent reports have …

Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity

YJ Zhang, YF Xu, C Cook, TF Gendron… - Proceedings of the …, 2009 - pnas.org
Inclusions of TAR DNA-binding protein-43 (TDP-43), a nuclear protein that regulates
transcription and RNA splicing, are the defining histopathological feature of frontotemporal lobar …

Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice

YF Xu, TF Gendron, YJ Zhang, WL Lin… - Journal of …, 2010 - jneurosci.org
Transactivation response DNA-binding protein 43 (TDP-43) is a principal component of
ubiquitinated inclusions in frontotemporal lobar degeneration with ubiquitin-positive inclusions …

ER–mitochondria associations are regulated by the VAPB–PTPIP51 interaction and are disrupted by ALS/FTD-associated TDP-43

…, KF Lau, G Vizcay-Barrena, WL Lin, YF Xu… - Nature …, 2014 - nature.com
Mitochondria and the endoplasmic reticulum (ER) form tight structural associations and these
facilitate a number of cellular functions. However, the mechanisms by which regions of the …