Chemistry and physics of a single atomic layer: strategies and challenges for functionalization of graphene and graphene-based materials
Graphene has attracted great interest for its superior physical, chemical, mechanical, and
electrical properties that enable a wide range of applications from electronics to …
electrical properties that enable a wide range of applications from electronics to …
Role of catalase in oxidative stress‐and age‐associated degenerative diseases
A Nandi, LJ Yan, CK Jana, N Das - Oxidative medicine and …, 2019 - Wiley Online Library
Reactive species produced in the cell during normal cellular metabolism can chemically react
with cellular biomolecules such as nucleic acids, proteins, and lipids, thereby causing their …
with cellular biomolecules such as nucleic acids, proteins, and lipids, thereby causing their …
Oxidative damage during aging targets mitochondrial aconitase
The mechanisms that cause aging are not well understood. The oxidative stress hypothesis
proposes that the changes associated with aging are a consequence of random oxidative …
proposes that the changes associated with aging are a consequence of random oxidative …
Pathogenesis of chronic hyperglycemia: from reductive stress to oxidative stress
LJ Yan - Journal of diabetes research, 2014 - Wiley Online Library
Chronic overnutrition creates chronic hyperglycemia that can gradually induce insulin resistance
and insulin secretion impairment. These disorders, if not intervened, will eventually be …
and insulin secretion impairment. These disorders, if not intervened, will eventually be …
Oxidative DNA damage and senescence of human diploid fibroblast cells.
Human diploid fibroblast cells cease growth in culture after a finite number of population
doublings. To address the cause of growth cessation in senescent IMR-90 human fibroblast cells…
doublings. To address the cause of growth cessation in senescent IMR-90 human fibroblast cells…
Synthesis of peptides and proteins without cysteine residues by native chemical ligation combined with desulfurization
LZ Yan, PE Dawson - Journal of the American Chemical Society, 2001 - ACS Publications
The highly chemoselective reaction between unprotected peptides bearing an N-terminal
Cys residue and a C-terminal thioester enables the total and semi-synthesis of complex …
Cys residue and a C-terminal thioester enables the total and semi-synthesis of complex …
Redox imbalance stress in diabetes mellitus: Role of the polyol pathway
L Yan - Animal models and experimental medicine, 2018 - Wiley Online Library
In diabetes mellitus, the polyol pathway is highly active and consumes approximately 30%
glucose in the body. This pathway contains 2 reactions catalyzed by aldose reductase (AR) …
glucose in the body. This pathway contains 2 reactions catalyzed by aldose reductase (AR) …
Microglia, neuroinflammation, and beta-amyloid protein in Alzheimer's disease
Z Cai, MD Hussain, LJ Yan - International Journal of Neuroscience, 2014 - Taylor & Francis
Compelling evidence from basic molecular biology has demonstrated the dual roles of
microglia in the pathogenesis of Alzheimer's disease (AD). On one hand, microglia are involved …
microglia in the pathogenesis of Alzheimer's disease (AD). On one hand, microglia are involved …
High-Throughput Synthesis of Single-Layer MoS2 Nanosheets as a Near-Infrared Photothermal-Triggered Drug Delivery for Effective Cancer Therapy
We report here a simple, high-yield yet low-cost approach to design single-layer MoS 2
nanosheets with controllable size via an improved oleum treatment exfoliation process. By …
nanosheets with controllable size via an improved oleum treatment exfoliation process. By …
Neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte ratio (PLR) were useful markers in assessment of inflammatory response and disease activity in SLE …
…, T Wei, M Yang, H Fu, Z Hu, Y Liang… - Modern …, 2016 - academic.oup.com
Objective: Although there have been extensive investigations on neutrophil to lymphocyte
ratio (NLR), platelet to lymphocyte ratio (PLR) and mean platelet volume (MPV) in many …
ratio (NLR), platelet to lymphocyte ratio (PLR) and mean platelet volume (MPV) in many …