Most tumor cells express antigens that can mediate recognition by host CD8 + T cells.
Cancers that are detected clinically must have evaded antitumor immune responses to grow …

Background The novel coronavirus SARS-CoV-2 is a newly emerging virus. The antibody
response in infected patients remains largely unknown, and the clinical value of antibody …

Investigations into the interaction between radiotherapy and the host immune system have
uncovered new mechanisms that can potentially be exploited to improve the efficacy of …

▪ Abstract The secondary lymphoid tissues are located at strategic sites where foreign antigens
can be efficiently brought together with immune system regulatory and effector cells. The …

The role of TGF-β-induced epithelial-mesenchymal transition (EMT) in cancer cell dissemination
is well established, but the involvement of lncRNAs in TGF-β signaling is still unknown. …

Recently, long noncoding RNAs (lncRNAs) were found to be dysregulated in a variety of
tumors. However, it remains unknown how and through what molecular mechanisms the …

Antibodies (Abs) that preferentially target oncogenic receptors have been increasingly used
for cancer therapy, but tumors often acquire intrinsic Ab resistance after prolonged and …

High-dose ionizing irradiation (IR) results in direct tumor cell death and augments tumor-specific
immunity, which enhances tumor control both locally and distantly. Unfortunately, local …

BACKGROUND & AIMS: Recent studies have suggested that CD4 + CD25 + regulatory T
cells (Treg) are increased and linked to compromised immune responses in patients with …

Ionizing radiation-mediated tumor regression depends on type I interferon (IFN) and the
adaptive immune response, but several pathways control I IFN induction. Here, we demonstrate …