Radiotherapy is one of the most common treatments for oral cancer. However, in the clinic,
recurrence and metastasis of oral cancer occur after radiotherapy, and the underlying …

Primary cilia and basal bodies are evolutionarily conserved organelles that mediate
communication between the intracellular and extracellular environments. Here we show that bbs1, …

In the ever-evolving landscape of cancer therapy, while cancer treatments such as
chemotherapy, radiotherapy, and targeted therapy aim to eradicate malignant cells, they also …

Background The faithful maintenance of DNA methylation homeostasis indispensably
requires DNA methyltransferase 1 (DNMT1) in cancer progression. We previously identified …

Joubert syndrome and related disorders (JSRD) are primarily autosomal-recessive conditions
characterized by hypotonia, ataxia, abnormal eye movements, and intellectual disability …

Autism is a multifactorial neurodevelopmental disorder affecting more males than females;
consequently, under a multifactorial genetic hypothesis, females are affected only when they …

Dramatic reductions in anthropogenic emissions during the lockdowns of the COVID‐19
pandemic provide an unparalleled opportunity to assess responses of the Earth system to …

Background The DiGeorge syndrome, the most common of the microdeletion syndromes,
affects multiple organs, including the heart, the nervous system, and the kidney. It is caused by …

Cilia are critical mediators of paracrine signaling; however, it is unknown whether proteins
that contribute to ciliopathies converge on multiple paracrine pathways through a common …

We performed whole genome sequencing in 16 unrelated patients with autosomal recessive
retinitis pigmentosa (ARRP), a disease characterized by progressive retinal degeneration …