Targeting Bcl-2-IP3 receptor interaction to reverse Bcl-2's inhibition of apoptotic calcium signals
YP Rong, AS Aromolaran, G Bultynck, F Zhong, X Li… - Molecular cell, 2008 - cell.com
The antiapoptotic protein Bcl-2 inhibits Ca 2+ release from the endoplasmic reticulum (ER).
One proposed mechanism involves an interaction of Bcl-2 with the inositol 1,4,5-…
One proposed mechanism involves an interaction of Bcl-2 with the inositol 1,4,5-…
Deep learning for air pollutant concentration prediction: A review
Air pollution has become one of the critical environmental problem in the 21st century and
has attracted worldwide attentions. To mitigate it, many researchers have investigated the …
has attracted worldwide attentions. To mitigate it, many researchers have investigated the …
The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor
YP Rong, G Bultynck, AS Aromolaran, F Zhong… - Proceedings of the …, 2009 - pnas.org
Although the presence of a BH4 domain distinguishes the antiapoptotic protein Bcl-2 from
its proapoptotic relatives, little is known about its function. BH4 deletion converts Bcl-2 into a …
its proapoptotic relatives, little is known about its function. BH4 deletion converts Bcl-2 into a …
Durvalumab versus placebo with chemoradiotherapy for locally advanced cervical cancer (CALLA): a randomised, double-blind, phase 3 trial
…, Y Kreynina, WF Cheng, F Rey, Y Rong… - The Lancet …, 2023 - thelancet.com
Background Concurrent chemoradiotherapy has been the standard of care for locally advanced
cervical cancer for over 20 years; however, 30–40% of treated patients have recurrence …
cervical cancer for over 20 years; however, 30–40% of treated patients have recurrence …
Evolutionary and biomedical implications of a Schistosoma japonicum complementary DNA resource
…, F Liu, ZD Zhu, HD Song, XR Xu, ZJ Wang, YP Rong… - Nature …, 2003 - nature.com
Schistosoma japonicum causes schistosomiasis in humans and livestock in the Asia-Pacific
region. Knowledge of the genome of this parasite should improve understanding of …
region. Knowledge of the genome of this parasite should improve understanding of …
Interrelated role of cigarette smoking, oxidative stress, and immune response in COPD and corresponding treatments
Cigarette smoking (CS) can impact the immune system and induce pulmonary disorders
such as chronic obstructive pulmonary disease (COPD), which is currently the fourth leading …
such as chronic obstructive pulmonary disease (COPD), which is currently the fourth leading …
The effects of shift work on sleeping quality, hypertension and diabetes in retired workers
Background Shift work has been associated with adverse health effects by disturbing circadian
rhythms. However,its potential long-term health effects and the persistent effects after …
rhythms. However,its potential long-term health effects and the persistent effects after …
DAPPLE: A pipelined data parallel approach for training large models
It is a challenging task to train large DNN models on sophisticated GPU platforms with
diversified interconnect capabilities. Recently, pipelined training has been proposed as an …
diversified interconnect capabilities. Recently, pipelined training has been proposed as an …
Adaptive radiation therapy (ART) strategies and technical considerations: a state of the ART review from NRG oncology
The integration of adaptive radiation therapy (ART), or modifying the treatment plan during
the treatment course, is becoming more widely available in clinical practice. ART offers strong …
the treatment course, is becoming more widely available in clinical practice. ART offers strong …
MATNet: A combining multi-attention and transformer network for hyperspectral image classification
Hyperspectral image (HSI) has rich spatial–spectral information, high spectral correlation,
and large redundancy between information. Due to the sparse background distribution of HSI, …
and large redundancy between information. Due to the sparse background distribution of HSI, …