New methods for preparation of tailor-made fluorine-containing compounds are in extremely
high demand in nearly every sector of chemical industry. The asymmetric construction of …

The healthspan of mice is enhanced by killing senescent cells using a transgenic suicide
gene. Achieving the same using small molecules would have a tremendous impact on quality …

The method of smoothed particle hydrodynamics (SPH) is extended to model incompressible
flows of low Reynolds number. For such flows, modification of the standard SPH formalism …

Clearing senescent cells extends healthspan in mice. Using a hypothesis‐driven
bioinformatics‐based approach, we recently identified pro‐survival pathways in human senescent …

Early detection and effective treatment of severe COVID-19 patients remain major challenges.
Here, we performed proteomic and metabolomic profiling of sera from 46 COVID-19 and …

Cerebral small vessel disease (SVD) is common during ageing and can present as stroke,
cognitive decline, neurobehavioural symptoms, or functional impairment. SVD frequently …

The ability to learn richer network representations generally boosts the performance of deep
learning models. To improve representation-learning in convolutional neural networks, we …

Hydrogen sulfide (H 2 S) is synthesized in the body from l‐cysteine by several enzymes
including cystathionine‐γ‐lyase (CSE). To date, there is little information about the potential role …

Aging is the largest risk factor for most chronic diseases, which account for the majority of
morbidity and health care expenditures in developed nations. New findings suggest that aging …

Idiopathic pulmonary fibrosis (IPF) is a fatal disease characterized by interstitial remodelling,
leading to compromised lung function. Cellular senescence markers are detectable within …