Strong association of de novo copy number mutations with autism
…, D Pai, R Zhang, YH Lee, J Hicks, SJ Spence, AT Lee… - Science, 2007 - science.org
We tested the hypothesis that de novo copy number variation (CNV) is associated with autism
spectrum disorders (ASDs). We performed comparative genomic hybridization (CGH) on …
spectrum disorders (ASDs). We performed comparative genomic hybridization (CGH) on …
The contribution of de novo coding mutations to autism spectrum disorder
…, B Ma, L Rodgers, J Troge, G Narzisi, S Yoon… - Nature, 2014 - nature.com
Whole exome sequencing has proven to be a powerful tool for understanding the genetic
architecture of human disease. Here we apply it to more than 2,500 simplex families, each …
architecture of human disease. Here we apply it to more than 2,500 simplex families, each …
Antimicrobial effects of silver nanoparticles
The antimicrobial effects of silver (Ag) ion or salts are well known, but the effects of Ag
nanoparticles on microorganisms and antimicrobial mechanism have not been revealed clearly. …
nanoparticles on microorganisms and antimicrobial mechanism have not been revealed clearly. …
[PDF][PDF] Increased risk of adefovir resistance in patients with lamivudine‐resistant chronic hepatitis B after 48 weeks of adefovir dipivoxil monotherapy
…, SW Jung, KM Kim, HC Lee, YH Chung, YS Lee… - …, 2006 - Wiley Online Library
Although adefovir dipivoxil (ADV) has a unique profile of delayed and infrequent resistance
in treatment‐naïve chronic hepatitis B patients, the association of ADV resistance with …
in treatment‐naïve chronic hepatitis B patients, the association of ADV resistance with …
De novo gene disruptions in children on the autistic spectrum
…, Z Wang, I Hakker, J Rosenbaum, B Yamrom, Y Lee… - Neuron, 2012 - cell.com
Exome sequencing of 343 families, each with a single child on the autism spectrum and at
least one unaffected sibling, reveal de novo small indels and point substitutions, which come …
least one unaffected sibling, reveal de novo small indels and point substitutions, which come …
Hepatocellular carcinoma: diagnostic performance of multidetector CT and MR imaging—a systematic review and meta-analysis
Purpose To perform a systematic review and meta-analysis of the diagnostic performance of
computed tomography (CT) and magnetic resonance (MR) imaging as noninvasive …
computed tomography (CT) and magnetic resonance (MR) imaging as noninvasive …
[HTML][HTML] Rare de novo and transmitted copy-number variation in autistic spectrum disorders
To explore the genetic contribution to autistic spectrum disorders (ASDs), we have studied
genomic copy-number variation in a large cohort of families with a single affected child and at …
genomic copy-number variation in a large cohort of families with a single affected child and at …
Microduplications of 16p11. 2 are associated with schizophrenia
…, G Kirov, AM Addington, J McClellan, S Yoon… - Nature …, 2009 - nature.com
Recurrent microdeletions and microduplications of a 600-kb genomic region of chromosome
16p11.2 have been implicated in childhood-onset developmental disorders 1 , 2 , 3 . We …
16p11.2 have been implicated in childhood-onset developmental disorders 1 , 2 , 3 . We …
Testing a tool for assessing the risk of bias for nonrandomized studies showed moderate reliability and promising validity
OBJECTIVES: To develop and validate a new risk-of-bias tool for nonrandomized studies (NRSs).
STUDY DESIGN AND SETTING: We developed the Risk of Bias Assessment Tool for …
STUDY DESIGN AND SETTING: We developed the Risk of Bias Assessment Tool for …
Parallel data processing with MapReduce: a survey
A prominent parallel data processing tool MapReduce is gaining significant momentum
from both industry and academia as the volume of data to analyze grows rapidly. While …
from both industry and academia as the volume of data to analyze grows rapidly. While …