A diacylglycerol lipase-CB2 cannabinoid pathway regulates adult subventricular zone neurogenesis in an age-dependent manner

MB Goncalves, P Suetterlin, P Yip… - Molecular and Cellular …, 2008 - Elsevier
… SVZ neurogenesis is of additional interest in … neurogenesis. Overall these data suggest that
a rundown in endocannabinoid tone might be responsible for the reduced SVZ neurogenesis …

[HTML][HTML] Brain-derived neurotrophic factor (BDNF) role in cannabinoid-mediated neurogenesis

FF Ferreira, FF Ribeiro, RS Rodrigues… - Frontiers in cellular …, 2018 - frontiersin.org
… cannabinoid receptors, we hypothesized that cannabinoid … BDNF signaling to fine-tune
neurogenesis. We show for the … the cannabinoid-mediated effects on SVZ and DG neurogenesis …

The endocannabinoid system and neurogenesis in health and disease

I Galve-Roperh, T Aguado, J Palazuelos… - The …, 2007 - journals.sagepub.com
… regarding the regulatory role of cannabinoids in neurogenesis and analyze them in the
context of those pathological disorders in which cannabinoid function and altered neuronal or …

Endocannabinoid system and adult neurogenesis: a focused review

S Oddi, L Scipioni, M Maccarrone - Current opinion in pharmacology, 2020 - Elsevier
… with embryonal neurogenesis. Accumulated preclinical evidence has indicated that eCBs
play a major role also in regulating adult neurogenesis. Increased cannabinoid receptor activity…

The anxiolytic effect of cannabidiol on chronically stressed mice depends on hippocampal neurogenesis: involvement of the endocannabinoid system

AC Campos, Z Ortega, J Palazuelos… - International Journal …, 2013 - academic.oup.com
… progenitor proliferation and neurogenesis in wild-type mice. … CBD-induced hippocampal
neurogenesis. CBD administration … the participation of the CB 1 cannabinoid receptor, as CBD …

Neural stem cell lineage-specific cannabinoid type-1 receptor regulates neurogenesis and plasticity in the adult mouse hippocampus

T Zimmermann, M Maroso, A Beer… - Cerebral …, 2018 - academic.oup.com
… cannabinoid type-1 receptor (CB1). To decipher whether CB1 regulates adult neurogenesis
… Deteriorated neurogenesis in NSC-specific CB1 knock-outs additionally resulted in reduced …

CB2 cannabinoid receptors promote neural progenitor cell proliferation via mTORC1 signaling

J Palazuelos, Z Ortega, J Díaz-Alonso… - Journal of Biological …, 2012 - jbc.org
… In particular, CB2 cannabinoid receptors have been shown to promote NP proliferation. …
neurogenesis by overcoming the undesired psychoactive effects of neuronal CB1 cannabinoid …

Role for neuronal nitric-oxide synthase in cannabinoid-induced neurogenesis

SH Kim, SJ Won, XO Mao, C Ledent, K Jin… - The Journal of …, 2006 - Elsevier
… -type mice, some of whom were given a cannabinoid agonist [R(+)-Win 55212-2] … cannabinoids
stimulate adult neurogenesis in DG and SVZ, at least partly by relieving the neurogenesis…

Cannabinoid agonist WIN-55,212-2 partially restores neurogenesis in the aged rat brain

Y Marchalant, HM Brothers, GL Wenk - Molecular psychiatry, 2009 - nature.com
… Our results confirm that neurogenesis is still present during … that neurogenesis in aged rats
can be significantly increased by a low, continuous, non-psychoactive dose of a cannabinoid …

ACEA (a highly selective cannabinoid CB1 receptor agonist) stimulates hippocampal neurogenesis in mice treated with antiepileptic drugs

M Andres-Mach, A Haratym-Maj, M Zagaja, R Rola… - brain research, 2015 - Elsevier
… Hippocampal neurogenesis plays a very important role in … and stimulate neurogenesis
with no side effects, cannabinoids … —a highly selective cannabinoid CB1 receptor agonist) …