Best e-Prescribing Software

Compare the Top e-Prescribing Software as of November 2025

What is e-Prescribing Software?

e-Prescribing software provides physicians and medical professionals with a platform to generate and send electronic prescription orders to pharmacies and their clients. Compare and read user reviews of the best e-Prescribing software currently available using the table below. This list is updated regularly.

  • 1
    RXNT

    RXNT

    RXNT

    RXNT is an ambulatory healthcare technology pioneer that empowers medical practices and healthcare organizations to succeed and scale through innovative, data-backed, AI-powered software. Our fully-integrated, ONC-certified suite of medical software—like Clinical EHRs, Practice Management, Medical Billing and RCM, E-Prescribing, Practice Scheduling, Patient Portal, and more—optimizes clinical outcomes and RCM for your practice. Used by tens of thousands of medical professionals—from large physician practices to medical billing companies—to drive growth, streamline business operations, and improve patient care across all 50 U.S. states. Our unified “Full Suite” system employs a secure, central database so your data passes through every product in real-time from anywhere, and more than 125 million prescriptions have been transmitted and over $7 billion in claims have been processed using RXNT.
    Starting Price: $118/month
    Partner badge
    View Software
    Visit Website
  • 2
    Valant Behavioral Health EHR

    Valant Behavioral Health EHR

    Valant Medical Solutions

    Provide exceptional, data-driven care from anywhere with Valant, the all-in-one EHR and practice management software designed exclusively for behavioral health practices of all sizes. - Focus the efforts of your entire workflow in one system built for individual psychotherapy, medication management, group counseling and more, whether delivered in person or virtually. - Speed your documentation process with 100+ clinical templates for evidence-based and specialized therapies, such as DBT, CBT, MFT, TMS, and weight and eating disorders. - Track your progress with 100+ comprehensive reports on patient retention, compliance, productivity, and financial performance. Demonstrate the value of your care to payers with 80+ reportable outcome measures you can schedule send to patients, auto-score, document, and track progress.
    View Software
    Visit Website
  • 3
    Foothold

    Foothold

    Foothold Technology

    Our human services software offers full functionality for case management, client tracking, electronic health record (EHR), and homeless information management (HMIS) all under one roof. We work with agencies across the spectrum of human services: including developmental disabilities, mental health, substance use disorder, homelessness, supportive housing, HCBS, and much more. Foothold is HIPAA-compliant mental health software, federally certified as an EHR, and offers full interoperability as you navigate the new landscape of care coordination and value-based care. Transform the way you provide care with nimble software and a partnership guided by experience.
  • 4
    AZZLY

    AZZLY

    AZZLY

    AZZLY Rize is the premier clinical and business platform for addiction treatment and mental health organizations. As an all-in-one substance use disorder and mental health specific EHR, Patient Engagement and RCM platform, we serve small, medium, and large clinics. Key features for OUTPATIENT Programs include: scheduling, appointment reminder, Zoom telehealth, treatment plans, progress notes, assessments and surveys. For RESIDENTIAL programs: census, medication management, bed board, withdrawal management, DrFirst e-prescribing, EPCS, PDMP, labs. For all levels of care: alerts, patient engagement portal, electronic billing and claims submission built in. AZZLY Rize empowers your staff through its 5 star training and support services, its simplicity and automation. As a true all-in-one EHR/PM/RCM platform, improved compliance, workflow and accurate billing are achieved real-time. We proudly serve programs in over 33 states and are hosted in Microsoft Azure's private cloud network.
    Starting Price: $50/user/month
  • 5
    OptiMantra

    OptiMantra

    OptiMantra

    OptiMantra is an EMR and practice management platform focused on helping integrative and wellness practices. It serves individual and multi-modality group practices of direct and primary care providers, acupuncturists, nurse practitioners, naturopaths, chiropractors, massage therapists, PTs, dieticians and nutritionists, aesthetics, and others across the US and Canada. It is a HIPAA and PHIPA-compliant platform and is highly adaptable and robust - it includes online appointment booking, patient messaging and email reminders, a patient portal, intake forms and customizable charting, integrated payment processing, integrated labs and imaging, insurance billing, in-program tele-health, inventory management, and more. The platform is cloud-based and accessible and usable via any desktop, laptop, tablet or phone with internet access.
    Starting Price: $99 per month
  • 6
    PracticeHarmony

    PracticeHarmony

    Mahler Health

    Practice Harmony is the premier practice management tool for running your healthcare practice. Our cloud-based practice management software solution streamlines your practice's operations and optimizes your workflow. Robust scheduling, advanced EHR, customized forms, patient dashboard, optimized voice-to-text, full RCM, TeleMedicine, TelePsychiatry, eRx, HIPAA Compliant CRM, and so much more. Streamlined operations require the perfect orchestration of efficient patient scheduling, proper documentation, and successful billing. Run your entire practice from scheduling to billing with just one log-in. Schedule a demo today to learn how you can bring Harmony to your Practice.
  • 7
    CarePaths EHR

    CarePaths EHR

    CarePaths

    We built CarePaths EHR for psychiatrists, psychologists, social workers, and counselors to affordably manage practices of all sizes. We are a HIPAA Compliant and ONC-Certified, fully integrated cloud-based behavioral electronic health record and practice management platform. Our system also includes online therapy with secure texting, teletherapy, and outcomes monitoring. With the free upgrade to CarePaths Connect, clinicians can also create a Digital Front Door, allowing patients to effortlessly sign up for services and book appointments with the CarePaths Connect mobile app for patients. Patients can also use the app to engage in teletherapy, message their therapist, and complete assessments. The Automated Measurement-Based Care (MBC) feature streamlines the process of outcomes monitoring so clinicians can tailor their approach based on patient feedback for better therapy outcomes.
    Starting Price: $49 per user per month
  • 8
    Ayfa iClinic

    Ayfa iClinic

    Ayfa iClinic

    Medical Software that organizes and streamlines your clinic. Have more practicality in your daily life with the software for clinics easier to use. Ayfa iClinic Teleconsultation. Orient your patients even from a distance iClinic Marketing. Send campaigns and email streams. Online Agenda. Access your medical schedule from anywhere. Customizable Medical Record. Leave your electronic medical record your way. We want your clinic to be as successful as you are. Ayfa iClinic is not just a system, we help you at all times of your day to day. Service agility. Quick support and tips to optimize your clinic. Access from anywhere. 00% data in the cloud, accessible from all devices. Bank security level. All data is encrypted and secure. Day-to-day practicality. UX team that produces the easiest-to-use system in Brazil. We have already helped over 70 thousand professionals in 22 countries and in all states of Brazil. Practically prove why Ayfa iClinic is more economical than staying on paper
    Starting Price: $79 per user, per month
  • 9
    DrChrono

    DrChrono

    DrChrono

    Increase the efficiency of your medical practice with an all-in-one practice management, electronic health records, and medical billing platform from DrChrono. With its modern and simple interface and dozens of advanced features, DrChrono empowers medical practitioners to better serve their patients. Users can easily schedule patient appointments, check and edit patient charts, and manage billing with ease.
  • 10
    AdvancedMD

    AdvancedMD

    AdvancedMD

    Enjoy ease of access and security without compromise. Work remotely, see patients and stay connected with a comprehensive cloud suite of office and remote care technologies. Since 1999 we are the only medical office software built on a 100% cloud platform. We are pleased to offer our entire suite of software and data storage on the Amazon Web Services (AWS) cloud hosting platform. Combined, AdvancedMD and AWS offer an unprecedented experience with fast, reliable access to all your information, unwavering data security, and simplified storage with automatic backup. No other ambulatory software system offers this standard of hosting, which means starting or growing your practice on the cloud is as easy and affordable as it gets. Because our software is hosted and managed on AWS, as part of your low monthly subscription you get the highest levels of reliability, security and performance. Our cloud platform makes our software simple to access across multiple devices and platforms.
  • 11
    iCare

    iCare

    iCare.com

    Finally, an Electronic Health Record system for hospitals, clinics, and practices that is flexible enough to change as healthcare evolves yet doesn’t cost a fortune to implement and operate. Delivered in the cloud, the iCare Enterprise Cloud EHR is a fully integrated system which includes a full range of administrative, clinical and revenue cycle management capabilities. iCare provides a complete solution for clinical, billing and administrative functionality at a fraction of the cost of legacy software. A web-based user interface not only gives your users access to iCare from any device but it also allows the workflows to be configured to the way clinicians work. Legacy EHR systems are built on outdated client-server systems that are costly, closed, inflexible and slow to innovate. iCare is built with the future in mind. The industry’s most modern architecture, intuitive user interfaces, and rock solid performance – no other EHR comes close to iCare.
  • 12
    InSync Healthcare Solutions

    InSync Healthcare Solutions

    InSync Healthcare Solutions

    InSync Healthcare Solutions EHR/PM enables healthcare professionals to provide healthcare that is in compliance with regulatory requirements. This ONC-ATCB certified and CCHIT certified ambulatory EHR and practice management (PM) product is for both solo practices and larger multi-specialty locations. InSync offers a choice between purchasing an upfront license or using a web-based subscription. Because InSync integrates both PM and EHR, this system delivers a medical office solution that eliminates the need for duplicate records and provides management and workflow throughout the practice. Features such as scheduling calendars, e-prescribing, electronic claims submission, quick physical exam charts, and reconciliation reports allow InSync’s system to be adaptable to any practice’s needs. In addition to its features, the package offers an intuitive user interface that enables users to create their own custom fields and customized layouts.
  • Previous
  • You're on page 1
  • Next