Best e-Prescribing Software

Compare the Top e-Prescribing Software as of November 2025

What is e-Prescribing Software?

e-Prescribing software provides physicians and medical professionals with a platform to generate and send electronic prescription orders to pharmacies and their clients. Compare and read user reviews of the best e-Prescribing software currently available using the table below. This list is updated regularly.

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    RXNT

    RXNT

    RXNT

    RXNT is an ambulatory healthcare technology pioneer that empowers medical practices and healthcare organizations to succeed and scale through innovative, data-backed, AI-powered software. Our fully-integrated, ONC-certified suite of medical software—like Clinical EHRs, Practice Management, Medical Billing and RCM, E-Prescribing, Practice Scheduling, Patient Portal, and more—optimizes clinical outcomes and RCM for your practice. Used by tens of thousands of medical professionals—from large physician practices to medical billing companies—to drive growth, streamline business operations, and improve patient care across all 50 U.S. states. Our unified “Full Suite” system employs a secure, central database so your data passes through every product in real-time from anywhere, and more than 125 million prescriptions have been transmitted and over $7 billion in claims have been processed using RXNT.
    Starting Price: $118/month
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  • 2
    Sevocity EHR
    If you're looking for a long-term, stable EHR company that gets to know and serve you and your practice, you've come to the right place. #1 rated implementation and the only EHR that offers free ongoing customization and personalized training by practice and provider, live US-based support 24/7/365 and affordable all-inclusive pricing.
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    Starting Price: $379.00/month
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  • 3
    Ayfa iClinic

    Ayfa iClinic

    Ayfa iClinic

    Medical Software that organizes and streamlines your clinic. Have more practicality in your daily life with the software for clinics easier to use. Ayfa iClinic Teleconsultation. Orient your patients even from a distance iClinic Marketing. Send campaigns and email streams. Online Agenda. Access your medical schedule from anywhere. Customizable Medical Record. Leave your electronic medical record your way. We want your clinic to be as successful as you are. Ayfa iClinic is not just a system, we help you at all times of your day to day. Service agility. Quick support and tips to optimize your clinic. Access from anywhere. 00% data in the cloud, accessible from all devices. Bank security level. All data is encrypted and secure. Day-to-day practicality. UX team that produces the easiest-to-use system in Brazil. We have already helped over 70 thousand professionals in 22 countries and in all states of Brazil. Practically prove why Ayfa iClinic is more economical than staying on paper
    Starting Price: $79 per user, per month
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    DrChrono

    DrChrono

    DrChrono

    Increase the efficiency of your medical practice with an all-in-one practice management, electronic health records, and medical billing platform from DrChrono. With its modern and simple interface and dozens of advanced features, DrChrono empowers medical practitioners to better serve their patients. Users can easily schedule patient appointments, check and edit patient charts, and manage billing with ease.
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    Nexus EHR

    Nexus EHR

    Nexus Clinical

    Nexus EHR is a cloud-based EHR and PM platform for clinical healthcare providers. Our EHR works with your clinical workflow and maximizes the physician-patient encounter. Access anywhere, any time, and with any device (PC, Tablet, Mobile). Breeze through encounters via our intuitive, easy-to-use interface that allows you to practice naturally. Multi-modal data input allows for maximum flexibility. Nexus Practice Management systems help you manage all billing activities, claims, and ERAs to maximize your revenues. Nexus EHR offers telemedicine to connect with your patients remotely. Nexus's Patient portal offers great flexibility to patients to fill all the demographics, insurance information, and histories online at their convenience.
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    Benchmark EHR

    Benchmark EHR

    Benchmark Solutions

    Benchmark EHR is a customizable system designed to save clinicians time and enhance patient care. It features configurable workflows, real-time coding recommendations, and ePrescriptions. Clinicians can generate and dictate progress notes during appointments, automatically updating patient records. The user-friendly patient portal allows patients to access lab results, refill prescriptions, message providers, check appointments, complete forms online, and more. Benchmark Solutions operates as healthcare practices’ one-stop management solution, comprising of Benchmark EHR software, Benchmark PM software, and Benchmark RCM services. Benchmark Solutions' offerings come together to form a comprehensive electronic toolset that can streamline daily internal operations and increase revenue earned all while improving the overall patient experience. Each piece of the Benchmark Solutions suite is modular so it can easily integrate with other technologies already in place.
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    Nextech

    Nextech

    Nextech Systems

    Revenue cycle management platform with payment processing, claims management, patient access, and denials management. Nextech’s specialty-focused technology solutions are personalized to meet the unique workflow requirements of specialty providers, helping practices increase efficiencies across their clinical, administrative, financial and marketing functions using a single platform. Offering all-in-one, ONC-certified electronic medical records (EMR/EHR), practice management, revenue management, and patient engagement software and services, Nextech is recognized as the top single solution provider for ophthalmology, plastic surgery and dermatology, serving a client base of more than 9,000 providers and 50,000 office staff members. Offering physicians intelligent healthcare technology, Nextech focuses on the success of its specialty practices through consultative guidance and implementation of solutions tailored to the speed and workflows of individual providers.
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