Best Endpoint Protection Software

Compare the Top Endpoint Protection Software as of November 2025

What is Endpoint Protection Software?

Endpoint protection software is a software platform that provides the solution to secure endpoints—such as laptops, desktops, smartphones, and tablets—against cyber threats and attacks. These platforms provide real-time monitoring and defense mechanisms to protect devices from malware, ransomware, phishing, and other types of threats. Endpoint protection software typically includes antivirus, anti-malware, firewall, encryption, and intrusion prevention features to prevent unauthorized access and ensure data security. It also allows for centralized management, enabling IT teams to enforce security policies, update software, and monitor the health of all devices in the network. By using endpoint protection software, organizations can safeguard their devices and networks from cyber risks while maintaining compliance with security standards. Compare and read user reviews of the best Endpoint Protection software currently available using the table below. This list is updated regularly.

  • 1
    Guardz

    Guardz

    Guardz

    Guardz is the unified cybersecurity platform purpose-built for MSPs. We consolidate the essential security controls, including identities, endpoints, email, awareness, and more, into one AI-native framework designed for operational efficiency. Our identity-centric approach connects the dots across vectors, reducing the gaps that siloed tools leave behind so MSPs can see, understand, and act on user risk in real time. Backed by an elite research and threat hunting team, Guardz strengthens detection across environments, turning signals into actionable insights. With 24/7 AI + human-led MDR, Guardz utilizes agentic AI to triage at machine speed while expert analysts validate, mitigate, and guide response, giving MSPs scalable protection without adding headcount. Our mission is simple: give MSPs the scale, confidence, and clarity they need to stay ahead of attackers and deliver protection to every SMB they serve.
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  • 2
    DriveStrike

    DriveStrike

    DriveStrike

    DriveStrike is easy to use, implement and manage. With DriveStrike you can execute secure remote wipe, remote lock, and remote locate commands on any platform. Integrated drive encryption support as well as mobile device management MDM for mobile platforms. Our professional support team is always available to answer your questions and help you install our services or manage your account and devices. Protecting your data and devices has never been easier or more cost effective. If you have questions or need help understanding how best to protect your data please contact us and we will gladly answer your questions. Protect your business with a device and data protection platform that keeps all devices safe with a single solution and Dashboard. Keep your Workstations, MacBooks, iPads, Smartphones, Tablets, Laptops safe, secure, and organized.
    Starting Price: $0.99 per month
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  • 3
    ThreatLocker

    ThreatLocker

    ThreatLocker

    The ThreatLocker suite of security tools are powerful and designed so that everyone from businesses to government agencies to academic institutions can directly control exactly what applications run on their networks. We envision a future in which all organizations can chart their own course free from the influence of cybercriminals and the damage their incursions cause, and our team of veteran cybersecurity professionals created ThreatLocker to make this vision a reality. The team at ThreatLocker has been developing cybersecurity tools for decades, including programs to enhance email and content security, and this is our most innovative and ambitious cybersecurity solution yet. We developed this unique cybersecurity system because we believe that organizations should have complete control of their networks and should not have to live in fear of the next malware attack. To learn more, visit ThreatLocker.com.
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  • 4
    NinjaOne

    NinjaOne

    NinjaOne

    NinjaOne enhances endpoint protection through monitoring, patching, and software controls. Automated alerts flag suspicious behavior or unauthorized applications. Regular patching keeps devices protected from vulnerabilities. Remote commands allow technicians to remediate threats instantly. Backup features add an extra layer of security against ransomware. Centralized reporting provides insights into endpoint security posture. NinjaOne ensures endpoints remain safe and compliant.
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    ConnectWise SIEM

    ConnectWise SIEM

    ConnectWise

    ConnectWise SIEM (formerly Perch) offers threat detection and response backed by an in-house Security Operations Center (SOC). Defend against business email compromise, account takeovers, and see beyond your network traffic. Our team of threat analysts does all the tedium for you, eliminating the noise and sending only identified and verified treats to action on. Built with multi-tenancy, ConnectWise SIEM helps you keep clients safe with the best threat intel on the market.
    Starting Price: $10 per month
  • 6
    Cynet All-in-One Cybersecurity Platform
    Cynet empowers MSPs and MSSPs with a comprehensive, fully managed cybersecurity platform that consolidates essential security functions into a single, easy-to-use solution. Cynet simplifies cybersecurity management, reduces operational overhead, and lowers costs by eliminating the need for multiple vendors and complex integrations. The platform provides multi-layered breach protection, offering robust security for endpoints, networks, and SaaS/Cloud environments. Cynet’s advanced automation streamlines incident response, ensuring rapid detection, prevention, and resolution of threats. Additionally, the platform is backed by Cynet’s 24/7 Security Operations Center (SOC), where the expert CyOps team delivers around-the-clock monitoring and support to safeguard all client environments. By partnering with Cynet, You can offer your clients advanced, proactive cybersecurity services while optimizing efficiency. Discover how Cynet can transform your security offerings today.
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    Syncro

    Syncro

    Syncro

    Syncro offers the first Extended Monitoring and Management (XMM) platform purpose-built for midsized MSPs and internal IT teams. The unified platform integrates RMM (endpoint management), professional services automation (PSA), and Microsoft 365 multi-tenant management to help organizations simplify operations, strengthen security, and scale profitably. Syncro delivers powerful automation, native AI capabilities, deep Microsoft 365 integration, and seamless support for 50+ third-party tools—enabling teams to reduce complexity, cut costs, and uncover new revenue opportunities. Its transparent per-user pricing model and commitment to continuous innovation make it an ideal solution for modern IT operations. Learn more at syncromsp.com or follow Syncro on LinkedIn.
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    Starting Price: $129 per user per month
  • 8
    Heimdal Endpoint Detection and Response (EDR)
    Heimdal® Endpoint Detection and Response is our proprietary multi-solution service providing unique prevention, threat-hunting, and remediation capabilities. It combines some of the most advanced threat-hunting technologies: - Next-Gen Antivirus - Privileged Access Management - Application Control - Ransomware Encryption Protection - Patch & Asset Management - Email Security - Remote Desktop - Threat Prevention ( DNS based ) - Threat Hunting & Action Center With 9 modules working together seamlessly under one convenient roof, all within one agent and one platform, Heimdal Endpoint Detection and Response grants you access to all the essential cybersecurity layers your business needs to protect itself against both known and unknown online and insider threats. Our state-of-the-art product empowers you to quickly and effortlessly respond to sophisticated malware with stunning accuracy, protecting your digital assets and your reputation in the process as well.
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    Starting Price: $0/month
  • 9
    Hexnode UEM

    Hexnode UEM

    Mitsogo Inc

    Hexnode, the enterprise software division of Mitsogo Inc., is a Unified Endpoint Management solution with cross-platform functionalities. Hexnode supports all major operating systems, including iOS, iPadOS, Android, Windows, macOS, tvOS, Linux, ChromeOS, visionOS, Apple TV, Android TV, and fireOS, and offers out-of-the-box enrollment methods. The entire device lifecycle, starting from enrollment to device retirement, can be monitored and managed from a unified console. Features such as automated device enrollment, geofencing, Remote Monitoring and Management, patch management, and a simple and intuitive UI makes it the perfect tool for device management. In addition, Hexnode offers a wealth of tools perfect for today's increasingly mobile, modern teams, which includes an intuitive dashboard for greater visibility and control over mobile devices across the enterprise, web filtering for security, location tracking, and so much more.
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    KernelCare Enterprise
    Global organizations trust TuxCare for live patching their critical Linux hosts and OT devices across their hybrid multi-cloud environments. No reboot is required to deploy and enable the TuxCare KernelCare Enterprise solutions to live patch Linux kernels and critical system libraries, including OpenSSL and Glibc. In contrast, all hosts and devices maintain the current production level uptime while receiving all security updates. TuxCare automates the patching process and eliminates the need to wait weeks or months for reboot cycles to apply patches. TuxCare currently protects over 1 million workloads worldwide. Tight integrations with popular patch management and vulnerability scanners, including Qualys, Crowdstrike, and Rapid7, enable TuxCare to fit seamlessly into existing infrastructure. The TuxCare secure patch server, ePortal, allows operations in gated and air-gapped environments. Reduce risk by significantly reducing the mean time to patch vulnerabilities
    Starting Price: $3.95 per month
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    Cisco Duo
    Cisco Duo is a cloud-based identity security solution that protects organizations from identity-based threats and boosts workforce productivity. Trusted by over 40,000 organizations worldwide, Duo delivers an exceptional access management experience across all users, devices, and applications, making access to resources secure, seamless, and easy. Duo with Cisco Identity Intelligence provides deep visibility across your identity ecosystem, adding a powerful security layer to any identity infrastructure. Offer users a world-class access experience through Duo Passport to eliminate MFA friction and fatigue without sacrificing security. To stop threats, Duo verifies user identities with strong authenticators including Duo passwordless, Verified Duo Push with number matching, and phishing-resistant factors like biometrics and FIDO2 security keys. Paired with deep insights into users’ devices, Duo gives you the control to adaptively limit access based on device health or user risk.
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    Starting Price: $3 per user per month
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    GoodAccess

    GoodAccess

    GoodAccess

    GoodAccess is a cybersecurity platform (SASE/SSE) that empowers medium-sized enterprises to easily implement Zero Trust Architecture (ZTA) in their infrastructure, regardless of its complexity or scale. By leveraging a Low-Code/No-Code approach, GoodAccess delivers a hardware-free, rapid deployment solution within hours or days, allowing companies to enhance their security without the need for in-house IT experts. Our platform ensures seamless integration with modern SaaS/cloud applications as well as legacy systems, protecting critical assets for remote and hybrid workforces. GoodAccess serves businesses with 50-5000 employees across diverse industries, particularly those adopting multi-cloud and SaaS environments. Start your 14-day full-featured free trial.
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    Starting Price: $7 per user/month
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    1Password

    1Password

    1Password

    1Password is a secure, scalable, and easy-to-use password manager that's trusted by the world's leading companies. Using 1Password makes it easy for your employees to stay safe online. Once 1Password is part of their workflow, good security habits will become second nature. 1Password Advanced Protection is now available with 1Password Business. Set Master Password policies, enforce two-factor authentication team-wide, restrict access with firewall rules, review sign-in attempts and require your team to use the latest version of 1Password. Our award-winning apps are available for Mac, iOS, Linux, Windows, and Android. 1Password syncs seamlessly across devices, so your employees always have access to their passwords. When everyone uses 1Password, your risk goes down — and your productivity goes up.
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    Starting Price: $3.99/month/user
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    SafeDNS

    SafeDNS

    SafeDNS

    At SafeDNS, we are committed to creating a safer and more secure online environment for SMBs, enterprises, ISPs, MSPs, OEMs, and Education. We have a global footprint, making the internet safer for millions of users in over 60 countries. With years of experience in the field of cybersecurity and DNS filtering, we offer cutting-edge solutions to safeguard your digital life. At present, SafeDNS serves more than 4000 businesses and institutions, and tens of thousands of home users worldwide. We do: -Web content filtering. We help you block all dangerous or unwanted websites such as pornography, violence, child sexual abuse and similar categories. -Malware protection. We also have your back against malicious sites trying to breach user devices either with viruses or information theft intent. -Cloud service. Additionally, we provide you with a cloud filtering service that requires no additional hardware purchase or software installation.
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    Starting Price: $0.9/user/month
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    Crashtest Security

    Crashtest Security

    Crashtest Security

    Crashtest Security is a SaaS-based security vulnerability scanner allowing agile development teams to ensure continuous security before even hitting Production. Our state-of-the-art dynamic application security testing (DAST) solution integrates seamlessly with your dev environment and protects multi-page and JavaScript apps, as well as microservices and APIs. Set up Crashtest Security Suite in minutes, get advanced crawling options, and automate your security. Whether you want to see vulnerabilities within the OWASP Top 10 or you want to go for deep scans, Crashtest Security is here to help you stay on top of your security and protect your code and customers.
    Starting Price: €35 per month
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    CrowdStrike Falcon
    CrowdStrike Falcon is a cloud-native cybersecurity platform that provides advanced protection against a wide range of cyber threats, including malware, ransomware, and sophisticated attacks. It leverages artificial intelligence (AI) and machine learning to detect and respond to threats in real time, offering endpoint protection, threat intelligence, and incident response capabilities. The platform uses a lightweight agent that continuously monitors endpoints for signs of malicious activity, providing visibility and protection without significant impact on system performance. Falcon’s cloud-based architecture ensures fast updates, scalability, and rapid threat response across large, distributed environments. Its comprehensive security features help organizations prevent, detect, and mitigate potential cyber risks, making it a powerful tool for modern enterprise cybersecurity.
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    KACE by Quest

    KACE by Quest

    Quest Software

    KACE® by Quest supports your unified endpoint management (UEM) strategy by helping you discover and track every device in your environment, automate administrative tasks, keep compliance requirements up-to-date and secure your network from a range of cyberthreats. Discover, manage and secure all your endpoints from one console as you co-manage your traditional and modern endpoints, including Windows, Mac, Linux, ChromeOS, and iOS and Android devices. KACE is a Unified Endpoint Management solution that offers a single point of control for managing IT systems across the entire organization, inside or outside your network. This comprehensive solution takes the stress out of keeping devices secure and compliant so you can do more.
    Starting Price: As low as $3/mo/device
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    Prey

    Prey

    Prey

    Prey is a cross-platform Device Tracking & Security tool to stay in control of remote assets. Mobile device tracking, management, and data protection available for laptops, tablets and mobiles. It offers a range of services for both personal and corporate use. The software and service are developed by the Chilean company Prey Inc., successor of the funding company Fork Ltd. Prey started in 2009 as a small tech company with a sole purpose: helping people keep track of their devices. 13 years later, our service evolved into a trusted multi-tool for both people and businesses. It's a service that protects over 8 million devices and their data every day, all around the world. We are experts at tracking, protecting and managing your work and play tech tools. And a proud team of people willing to support you.
    Starting Price: $1.2 per month
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    Xcitium

    Xcitium

    Xcitium

    Xcitium is the only unified zero-trust cybersecurity platform, bringing zero-trust posture all the way from endpoints to the cloud under a single pane of glass. With Xcitium, we protect with detection-less innovation: patented Kernel-level API virtualization. Xcitium reduces the amount of time a threat can maneuver or dwell in your environment, down to absolute zero. Attacks happen in minutes and seconds. However, the impact of an attack does not always occur instantly. It can take some dwell time for an intruder to get a foothold and to execute search and destroy or exfiltration missions. Xcitium intercepts and isolates the attack before any of its impact and intended damage can occur. Equip every endpoint, network, and workload with the latest threat intelligence against cyber threat signatures and payloads. Defense against new or zero-day cyber threats using powerful static, dynamic, and patented behavioral AI.
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    Carbon Black EDR
    Carbon Black Endpoint Detection and Response (EDR) by Broadcom offers a comprehensive solution for detecting, investigating, and responding to cybersecurity threats on endpoints. It utilizes advanced behavioral analysis and machine learning to identify suspicious activities in real time, providing security teams with actionable insights to prevent data breaches and mitigate risks. With its cloud-based architecture, Carbon Black EDR enables continuous monitoring, visibility into endpoint activity, and automated threat response. It’s designed to support organizations of all sizes by improving threat detection, reducing investigation time, and enhancing overall endpoint security.
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    AhsayCBS

    AhsayCBS

    Ahsay Systems Corporation Limited

    Ahsay Backup Software is specifically designed for Managed Service Providers, System Integrators, or IT Consulting Companies. It enables them to offer secure managed, cloud-hosted, and on-premises backup services to clients and earn a stable recurring income. The whole solution is built on a client-server architecture: The server-side centralized management console (AhsayCBS) can be installed on your backup server hosted in your data center or on a cloud platform like Microsoft Azure. We offer a hosted AhsayCBS instance if you don't want to host it. On the client side, there are three backup agents: AhsayOBM, AhsayACB, and Ahsay Mobile, which you can install on your customers' endpoints and devices. AhsayOBM backs up servers, databases, virtual machines, NAS devices, and Microsoft 365 user accounts as an administrator; AhsayACB backs up files on desktops, laptops, and Microsoft 365 as individual users. 
    Starting Price: $1.50 / month
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    VIPRE Endpoint Security

    VIPRE Endpoint Security

    VIPRE Security Group

    VIPRE Endpoint delivers comprehensive defense against today’s sophisticated malware without the complexity of other solutions. We keep your total cost of ownership low while providing advanced security powered by machine learning, real-time behavioral analysis, and a global threat intelligence network. VIPRE combines a modern endpoint solution with time-saving efficiencies, ensuring your organization stays secure and operational. Protecting files, applications, and networks, VIPRE offers complete malware defense. It also helps enforce internet usage policies with granular controls that support employer duty-of-care. Dynamic dashboards provide real-time insights into the status of your endpoint environment, making it easier to monitor and manage security across your organization. Available as a core next-generation AV solution, a full EDR solution, or a combined EDR+MDR solution, we have a package that will work for you.
    Starting Price: $34/seat/year
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    Apozy Airlock
    Apozy Airlock. The browser endpoint detection and response platform that neutralizes web attacks in one click. The Internet is a dangerous place. It doesn’t have to be. Airlock fills the gap in your EPP/EDR by protecting the browser, delivering a safe, clean, and lightning-fast internet experience. Powered by the very first visually-aware native browser isolation platform with over 6 petabytes of visual data, Airlock prevents web attacks in real time. Airlock stops spearfishing in its tracks. With a visual model database of over 67.83 billion pages which analyzes over 12.20 trillion links per year, our technology protects anyone clicking on a malicious link by sandboxing the threat.
    Starting Price: $9/month/user
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    WithSecure Elements XDR
    WithSecure Elements Cloud seamlessly integrates software, services, and all essential security capabilities into a single unified solution. WithSecure's modular Elements Cloud cyber security platform seamlessly integrates Extended Detection and Response (XDR), Exposure Management (XM) and Co-Security Services into a single unified solution. WithSecure Elements XDR includes Elements Endpoint Security (EPP+EDR), Identity Security for Microsoft Entra ID, Collaboration Protection for Microsoft 365, and Cloud Security as modules. WithSecure Elements Exposure Management (XM) is a continuous and proactive solution that predicts and prevents breaches against your company’s assets and business operations. At WithSecure, we've spent more than 35 years providing enterprise-grade cyber security that aligns with business goals, making us your ideal strategic cyber security partner. Embracing 'The European Way' of trust and compliance, we protect and enable operations across all industries.
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    Defense.com

    Defense.com

    Defense.com

    Take control of cyber threats. Identify, prioritize and track all your security threats with Defense.com. Simplify your cyber threat management. Detection, protection, remediation, and compliance, are all in one place. Make intelligent decisions about your security with automatically prioritized and tracked threats. Improve your security by following the effective remediation steps provided for each threat. Gain knowledge and advice from experienced cyber and compliance consultants when you need assistance. Take control of your cyber security with easy-to-use tools that can work with your existing security investment. Live data from penetration tests, VA scans, threat intelligence and more all feeds into a central dashboard, showing you exactly where your risks are and their severity. Remediation advice is included for each threat, making it easy to make effective security improvements. Powerful threat intelligence feeds are mapped to your unique attack surface.
    Starting Price: $30 per node per month
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    UpGuard

    UpGuard

    UpGuard

    The new standard in third-party risk and attack surface management. UpGuard is the best platform for securing your organization’s sensitive data. Our security ratings engine monitors millions of companies and billions of data points every day. Continuously monitor your vendors, automate security questionnaires, and reduce third and fourth-party risk. Monitor your attack surface, prevent data breaches, discover leaked credentials, and protect customer data. Scale your third-party risk program with UpGuard analysts, and let us monitor your organization and vendors for data leaks. UpGuard builds the most powerful and flexible tools for cybersecurity. Whether you’re looking to prevent third-party data breaches, continuously monitor your vendors, or understand your attack surface, UpGuard’s meticulously designed platform, and unmatched functionality helps you protect your most sensitive data. Hundreds of the world’s most data-conscious companies are scaling faster and more securely.
    Starting Price: $5,249 per year
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    SafeConsole

    SafeConsole

    DataLocker

    Central Management Server Software. Instantly gain complete and granular control over all of your encrypted USB flash drives and portable hard drives with the SafeConsole central management server software: Achieve compliance for USB storage usage, with full control and audit. Keep the productivity benefits of USB storage devices – without the risks of malware, data leaks and breaches. Available as an on-premises software or as a DataLocker hosted cloud service with worldwide locations. Enforce policies such as password rules, file-type restrictions or geographic boundaries. Reset passwords, switch devices into read-only mode, and even remotely wipe them in case of loss or theft. Monitor all your encrypted drives, including their location anywhere in the world. Integrate with Active Directory to track users, assigned devices and connected computers with ease. See which files are saved to or deleted from your encrypted drives at any given moment.
    Starting Price: $28 per device per year
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    IGEL

    IGEL

    IGEL Technology

    IGEL provides the next-gen edge OS for cloud workspaces. Our solutions offer you extreme CAPEX hardware cost savings, sharply reduced ongoing operating expenses, and a more secure and manageable endpoint management and control platform across nearly any x86 device. Work is now defined by what we do, not where we go. The widely distributed workforce is here to stay, and IGEL OS allows people to thrive in their work from anywhere, while organizations retain full management, control, and security of user endpoints regardless of which endpoint device they use. IGEL OS secures and simplifies digital workspaces in healthcare, finance, retail, higher education, government, and manufacturing organizations around the world. Its 100+ technology integrations lend full support of the latest unified communications tools, VDI platforms, DaaS, and SaaS-based applications from anywhere on any x86-64 device, including thin client, laptop, or tablet.
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    HCL BigFix

    HCL BigFix

    HCL Software

    "HCL BigFix: Secure Resilient Operations, Powered by AI HCL BigFix is the platform for unified endpoint and infrastructure management, purpose-built to deliver on the Digital+ promise of reducing cost, risk, and complexity. Proven at enterprise scale, BigFix secures and manages 155M+ endpoints across nearly 100 operating systems. It leverages AI-driven automation to deliver continuous compliance and real-time vulnerability remediation with one of the industry’s best first-pass patch success rates (>98%). This is enhanced by AEX, our agentic AI platform, which transforms the digital employee experience through proactive, self-healing support. HCL BigFix is the single solution to secure any endpoint, in any cloud, across any industry. "
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    Trend Micro ServerProtect
    Enterprise servers can be a vulnerable, centralized point of information exchange. Even from inside the network, users or applications without adequate protection can unintentionally upload infected files to the server, which can spread to other systems that access these files. Additionally, large organizations may have hundreds or thousands of individual server machines that require monitoring, configuration, and maintenance. More importantly, today’s sophisticated attacks can target multiple points on the network and leave unseen trails of damage and the potential for re-infection. Trend Micro™ ServerProtect™ delivers the industry’s most reliable virus, spyware and rootkit protection while simplifying and automating security operations on servers. ServerProtect scans and detects malware in real time and incorporates cleanup capabilities to help remove malicious code and repair system damage.
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