Compare the Top EDI Software in the USA as of November 2025

What is EDI Software in the USA?

EDI (Electronic Data Interchange) software is software that automates the exchange of business documents, such as invoices, purchase orders, and shipping notices, between companies in standardized electronic formats. It eliminates the need for manual data entry, reducing errors and improving the speed and accuracy of business transactions. EDI providers offer platforms and services that facilitate this seamless data exchange, integrating with existing ERP systems and ensuring compliance with industry standards. These providers also offer support for different communication protocols and data formats, enabling businesses to connect with various trading partners efficiently. By using EDI software and working with EDI providers, companies can streamline their supply chain operations, enhance collaboration, and reduce operational costs. Compare and read user reviews of the best EDI software in the USA currently available using the table below. This list is updated regularly.

  • 1
    TrueCommerce

    TrueCommerce

    TrueCommerce

    TrueCommerce is the only electronic data interchange (EDI) provider that offers a true one-stop shopping solution for EDI compliance. Affordable, robust, and easy-to-use, TrueCommerce EDI Solution streamlines order processing, reduces manual data-entry errors, and increases employee productivity. The company's core software product, TrueCommerce EDI Transaction Manager, supports any trading partner using ANSI ASC X12 EDI standards and converts business documents (e.g. purchase orders and invoices) into an EDI-compliant format.
  • 2
    Cin7 Inventory Management
    Cin7 is a web based inventory system that helps businesses manage their inventory anywhere, in real time. Suitable for omni-channel retailers and wholesalers, Cin7 integrates cloud inventory, Point of Sale, warehouse management, B2B ecommerce, 3PL, and direct EDI, in one robust platform. Cin7 also features seamless integrations for Shopify, Magento, Xero, Amazon, Ebay and more.
  • 3
    EDI Power Reader

    EDI Power Reader

    EMS Healthcare Informatics

    EMS Healthcare Informatics provides effective middleware software, end-user-friendly EDI utilities, and custom application development for the healthcare industry. We specialize in the HIPAA transaction sets and focus on delivering actionable business data to the users. We have clients all over the United States, and in virtually every sub-industry of healthcare including those on the provider-side, the payer-side, as well as the extensive 3rd party community. EMS is a niche healthcare information technology firm that provides solutions for financial/administrative and clinical electronic transactions, full implementation and support services. EMS has been serving the needs of Healthcare Business and IT professionals since 1996. In addition to the EDI Power Tools Suite of readily deployable software utilities, EMS also develops custom applications tailored specifically to your needs: from unique single-purpose utilities, to Custom Enterprise Applications.
  • 4
    Missing Link
    Missing Link is a procurement-to-payment data switching provider, connecting suppliers and customers across all industries. We help our clients refine, digitalize and manage their entire procurement process, saving them time, money - and many headaches! There’s no need for you to have dedicated staff to configure, manage and support individual connections to every one of your customers and suppliers. Connect to us and we’ll handle every procurement transaction for you. We cover the entire procurement process, from onboarding of your trading partners to daily management and support. Our skills range from business analytics and project management, to high-level technical as well as support center staff. Missing Link facilitates all data formats and messaging types. This means that customers and suppliers don’t have to conform to each other’s software and system requirements. Anyone can do business.
    Starting Price: $1000 per month
  • 5
    EDIConnect
    EDIConnect is a complete solution created to build bi-directional electronic data interchange (EDI) integration. Developed by Astera, EDIConnect allows businesses to exchange invoices, purchase orders, advance ship notices, and other business documents directly from one system to the other. EDIConnect delivers the scalability and the capability to meet the ever-changing EDI needs of businesses with its powerful visual tools and built-in transaction sets for advanced data mapping, incoming file translation and ingestion, and more. By leveraging EDIConnect, users can effortlessly manage data ingestion as well as deliver fast and efficient acknowledgment generation, outgoing transaction construction, and automation, process orchestration, and scheduling.
  • 6
    SBI Software

    SBI Software

    SBI Software

    SBI Software’s tools for big retailers are built for big retail suppliers and buyers to improve your complex business process. When you partner with SBI, you are leveraging our expert team of national market researchers and industry experts. Founded in 2000, SBI Software now partners with some of the largest global retailers in 46 states and 5 countries. SBI clients alone are doing 1.2 billion in annual sales. Running debt-free with no outside investors, SBI is focused on speed in innovation and high-quality service. A new cost-free feature to process credit cards, debit cards, and ACH payments using Cloud-based technology. Our fully-integrated desktop ERP software is specifically built for big retail suppliers. Get complete visibility, from Forecasting to Order Fulfillment. Live availability from over 27 different green goods suppliers. Integrated with SBI’s Desktop ERP, giving growers the most powerful ordering experience yet.
  • 7
    Nipendo

    Nipendo

    Nipendo

    Nipendo has been revolutionizing the way enterprises conduct and manage procurement, supply chain and finance processes for over a decade, with our cloud-based RPA (Robotic Process Automation) platform for Purchase-to-Pay (P2P) process automation. The platform streamlines and simplifies interactions between enterprises (buyers) and their suppliers across all spend categories of goods and services, and all supplier types and sizes. Using RPA, Machine Learning and AI technologies, the platform makes P2P processes touch-free and error-free and provides process governance, compliance management and enforcement, audit and validation, dispute resolution and discrepancy management. Our technology does not replace existing P2P processes or ERP systems, neither on the Buyer’s side nor on the supplier’s, we extend their capabilities by automating all P2P processes, thereby providing you with a better way of doing business, greater efficiencies and dramatic cost savings.
  • 8
    iR*EDI

    iR*EDI

    Radley Corporation

    Reduce or end manual tasks while meeting compliance standards. For example, schedule repetitive tasks directly from iR*EDI. Also, automate labeling and shipping for pallets, containers, and parts. Streamline communications while improving customer service and managing your suppliers. Plus, gain real-time visibility into key data, errors, and events. See your important KPIs through Radley’s configurable dashboard. With Radley, you’re always compliant with trading partner requirements. We format your EDI transactions to your partners’ unique EDI specifications. Then, if those specifications change, we automatically update the maps. We’ll handle all aspects of your project, from mapping to translation. Our expert team has decades of EDI experience with manufacturers all over the world. Put our B2B eCommerce experience to work for you! B2B EDI software automates business transactions, eliminating time-consuming manual tasks.
  • 9
    Relasoft EDI

    Relasoft EDI

    Relasoft Solutions

    The solution fully automates both EDI and manual purchase order processing, and takes care EDI 850, 855, 856 and 810. All compliance requirements of pharmaceutical industry are fully implemented. The solution knows how to interact with third-party logistics companies, and comes fully configured for almost all pharmaceutical wholesalers and many direct buyers. The solution can be used by other companies.
    Starting Price: $2,000 per company
  • 10
    Commport Integrated EDI

    Commport Integrated EDI

    Commport Communications

    Commport’s Integrated EDI solution translates your inbound documents, like purchase orders, from your trading partners’ EDI files into a format that can be imported directly into your ERP, accounting, or other business system. When you’re ready to send out invoices, PO acknowledgments, or other outbound documents, Commport takes the format exported from your system and translates it into the EDI formats required by your trading partners. Translation is fast and reliable – so you can focus on your business while Commport takes care of your EDI needs. Key Features: 1. Integrate business documents with your internal operations using Commport’s extensive library of plug-ins for mid-market and higher business systems. 2. User visibility into activity on the Commport Network through Commport Monitor and Commport Portal. 3. Achieve seamless translation, converting business system documents into global standards-compliant documents. 4. Connect to the powerful Commport VAN
  • 11
    Radley EDI Solutions
    Put Radley's 45 years of EDI experience to work for you! Radley’s platform of EDI solutions lets you simplify communications with your trading partners and manage repetitive activities like purchase orders, ship notices and invoices. Replace emails, phone calls and paper-based exchanges to increase speed and accuracy, while lowering costs. Radley EDI supports any trading partner using ANSI ASC X12 EDI standards and converts business documents into an EDI-compliant format. We put our 4 decades of expertise to work for you, ensuring the best EDI services for your unique industry, workflows and trading partner requirements. Choose the EDI deployment option that’s right for you: Hosted, On Premise or Cloud Based. You can be confident that Radley will help you select the right solution for your business, with easy implementation and best-in-class support. - Fixed-fee Mapping - Transaction Archives & Reprocessing - Optional EDI Management - VAN Services - Full Dashboard Visibility
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