Compare the Top EDI Software in the USA as of November 2025

What is EDI Software in the USA?

EDI (Electronic Data Interchange) software is software that automates the exchange of business documents, such as invoices, purchase orders, and shipping notices, between companies in standardized electronic formats. It eliminates the need for manual data entry, reducing errors and improving the speed and accuracy of business transactions. EDI providers offer platforms and services that facilitate this seamless data exchange, integrating with existing ERP systems and ensuring compliance with industry standards. These providers also offer support for different communication protocols and data formats, enabling businesses to connect with various trading partners efficiently. By using EDI software and working with EDI providers, companies can streamline their supply chain operations, enhance collaboration, and reduce operational costs. Compare and read user reviews of the best EDI software in the USA currently available using the table below. This list is updated regularly.

  • 1
    GoAnywhere MFT
    GoAnywhere MFT provides secure managed file transfer for enterprises. Deployable on-premise, in the cloud, or in hybrid environments, GoAnywhere MFT software enables organizations to exchange data among employees, customers, and trading partners, as well as between systems, securely. GoAnywhere MFT was a recipient of the Cybersecurity Excellence Award for Secure File Transfer.
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  • 2
    Files.com

    Files.com

    Files.com

    6,000+ companies trust Files.com to automate and secure business critical transfers. We obsess about security, compliance, reliability, and performance so your critical business processes just work every time. Easily manage any transfer flow without writing scripts or code, and onboard workloads and partners effortlessly. We support standard file transfer protocols (FTP, SFTP, AS2) for working with external partners and also provide native apps for high performance internal transfers. As a fully Cloud-Native SaaS, there are no servers for you to buy or maintain, there is no installation required, and high availability and redundancy are built in and free. Out-of-the-box integrations include Microsoft (Azure, SharePoint, OneDrive, Active Directory & Office), AWS (S3 & SNS), Google (Cloud & Drive), Box, Dropbox, Zapier, and dozens of others. Developers can leverage our SDKs, API, and CLI to build custom integrations too.
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  • 3
    JSCAPE MFT Server

    JSCAPE MFT Server

    Redwood Software

    Platform Independent Managed File Transfer Server. JSCAPE is the perfect solution for businesses and government agencies looking to centralize your processes and provide secure, seamless and reliable file transfers. Meet all compliance regulations including PCI DSS, SOX, HIPAA and GLBA. Centralize and gain control of file transfers to meet challenging business requirements. Deploy in the cloud, on-premise or in a hybrid cloud environment. Triggers are used to automate various business processes without the need to write custom scripts. Exchange files with JSCAPE's free Android and iOS file transfer clients. Integrate with Amazon, Google and Microsoft regulatory compliance. Get powerful and flexible user authentication mobile support for iOS and Android devices.
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  • 4
    Cleo Integration Cloud
    Cleo Integration Cloud (CIC) award-winning EDI software that enables the best B2B integration, visibility and control. CIC accelerates EDI automation, expedites partner onboarding, and easily tackles EDI issue resolution. Bringing end-to-end integration visibility across EDI, non-EDI, and API integrations enabling you to grow your revenue-generating business processes better and faster. CIC is optimizing thousands of supply chains for logistics providers, manufacturers, and wholesalers. Encompassing seamless ERP integration, WMS integration, TMS integration and more, our cloud-based B2B integration platform transforms costly, complicated processes into truly efficient, agile, and scalable operations. Our ecosystem integration approach offers the best B2B capabilities so you can automate EDI and API transactions, rapidly onboard partners, and gain competitive control.
  • 5
    AS2 Gateway

    AS2 Gateway

    Aayu Technologies LLC

    Assured Trading with AS2 to Digitalize your Business. AS2 Gateway provides a B2B trading platform for organizations trading over the AS2 protocol, with a simplified and intuitive interface concealing the underlying complexities from end users. AS2 Gateway is fully compliant with the AS2 specification published by Drummond and Morberg, while ensuring the security of exchanged data via encryption, digital signature validation and guaranteed integrity through MIC (Message Integrity Check) hashing. Data security is further enhanced by utilizing the latest SSL/TLS channelling technologies as a supplementary security standard.
    Starting Price: $59 per month
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