Compare the Top Safety Data Sheet (SDS) Software for Mac as of November 2025

What is Safety Data Sheet (SDS) Software for Mac?

Safety Data Sheet (SDS) software is designed to manage, store, and track Safety Data Sheets, which contain critical information about hazardous chemicals and materials. It simplifies compliance with safety regulations by organizing SDS documents in a centralized, digital repository accessible to all employees. With features like automated updates, version control, and quick search functionality, SDS software ensures that workers have immediate access to the latest safety information. Many solutions also offer reporting and tracking capabilities to monitor chemical inventory and flag potential risks. Ultimately, SDS software enhances workplace safety, ensures regulatory compliance, and minimizes the administrative burden of manual SDS management. Compare and read user reviews of the best Safety Data Sheet (SDS) software for Mac currently available using the table below. This list is updated regularly.

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    VelocityEHS

    VelocityEHS

    VelocityEHS

    We deliver EHS management software that solves complex business challenges in simple ways. Our implementations are quicker, cost less and are more successful than traditional enterprise software systems. The real value of our solution is not the software itself, but how well it helps you do your job and achieve your goals — across departments, facilities, locations, and continents. Our true cloud solutions are simple enough for your frontline people to use on the fly, and sophisticated enough for you to run global, best-in-class programs — right out of the box. VelocityEHS brings together the industry’s most trusted solutions for managing risk, industrial hygiene, environmental concerns, hazards and incidents, training and much more. And we are the only source for MSDSonline chemical management and Humantech industrial and office ergonomics solutions. See why more than 18,000 customers worldwide trust us to simplify their complex compliance challenges.
  • 2
    iChemistry

    iChemistry

    Intersolia

    Since 1999, we’ve been providing our customers with the market’s most complete chemical management solution, developed in collaboration with our customers and our market-leading experts. iChemistry is our cloud-based solution for the end users in the chemical management supply chain. Our software helps you manage environmental, health, and safety performance, ensure compliance, minimize risk, and improve profitability. Create and distribute safety sheets so that you can identify risks, prevent accidents, and reduce workplace hazards. Comply with government requirements such as REACH or GHS. Become more sustainable by working proactively to reduce hazardous chemicals. Increase efficiency and control, so that you can free up more time and resources. With iChemistry, you also get access to our integrated SDS service that has one of Europe’s largest databases for safety data sheets. All of our SDS are digitized, which means that you get instant access to all essential information.
    Starting Price: Free
  • 3
    Vector EHS

    Vector EHS

    Vector Solutions

    The most cost-effective leader in EHS Management for over 15 years. Track essential EHS data via the web or on your mobile device with our comprehensive safety software suite. No matter the size, industry, or safety program, Vector EHS can be configured to meet your organization's needs. With an easy-to-use interface and highly praised customer support, managing your safety data will never be easier. Our EHS software is easy to use and allows all organizations, from global leaders to local businesses, to track, manage and comply with safety, environmental, and health regulations. Capabilities include: Incident Reporting, Mobile Inspections, Safety Metrics & Reports, Behavior Based Safety, Hazard Reporting, Job Safety Analysis, Online Employee Training, SDS & Chemical Management, and more. Vector EHS Management Software is built to meet the needs of some of the world's most critical industries.
  • 4
    EHS Insight

    EHS Insight

    EHS Insight

    EHS Insight is an environmental, health and safety (EHS) management platform that empowers organizations to ensure company-wide compliance. Affordable and quick to setup, EHS Insight offers the best value in EHS software today by providing businesses with the tools they need to manage incidents, audits and inspections, compliance obligations, corrective actions and more. EHS Insight also comes with fantastic support to assist businesses during and after software implementation.
    Starting Price: $200.00/month
  • 5
    CHEMDOX

    CHEMDOX

    CHEMDOX

    CHEMDOX® software supports regulatory experts in all aspects of hazardous materials management: - Chemical Management - Safety Data Sheet (SDS / MSDS) Authoring - Safety Data Sheet (SDS) Translation - Hazard Labeling - GHS Compliance - Safety Data Sheet (SDS) Distribution CHEMDOX® supports high-quality classifications with strong regulatory content and includes classification calculators for all included regulations. With CHEMDOX®, many hazardous materials management processes are automated and performed with database support.
  • 6
    Knowella

    Knowella

    Knowella

    Knowella’s enterprise-grade SaaS platform empowers companies to build no-code apps for efficient operations, safety, quality, and compliance management. Powered by configurable form builders, QR codes, AI-driven cameras, and data-capturing drones, Knowella streamlines operations, safety, quality, and supply chain management. With 100+ pre-built programs, it’s your AI-powered solution for operational excellence.
    Starting Price: $10/user/month
  • 7
    ExESS

    ExESS

    Lisam Systems

    ExESS® provides users a comprehensive and globally compliant solution for the authoring and distribution of safety data sheets. Built on flexible and scalable Microsoft .NET technology, ExESS is user friendly and can be installed on single workstations, over worldwide corporate networks or accessed and used via the cloud. In addition, country specific classifications such as the Austrian, VbF, the German; BetrSichV, Störfallverordnung and WGK, VOCs for EU, US and Swiss VOCV as well as Danish MAL and the US; NFPA and HMIS ratings are also provided in ExESS. Further, Lisam provides occupational exposure limit values and caters for biological limit values, SEVESO etc. The ExESS classification view allows users to review the actual calculation and data (including source) used to come to a final classification result.
  • 8
    SpheraCloud
    Empower your business with actionable and measurable results and gain a comprehensive view of ESG performance and risk in real time. For generations, companies found it near-impossible to generate a holistic view of their risk profiles. Today, they have SpheraCloud®, an integrated ESG performance and risk management software platform. SpheraCloud is a key part of Sphera’s approach to addressing safety and sustainability issues before they even occur. It allows users to not only get the right information to the right people at the right time, but also empowers them to make better business decisions with its predictive and prescriptive capabilities. Many companies struggle to connect disparate data throughout their organizations and their value chains, and to communicate that risk efficiently and effectively. It’s hard to complete such an enormous task—without SpheraCloud. The innovative SaaS platform empowers your company to gain a comprehensive view of ESG performance and risk.
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