World's FirstCDK2/4/6 Inhibitor Approved for Marketing, Culmerciclib Capsules (Saitanxin®) Reshape the Breast Cancer Treatment Landscape... Culmerciclib is a First-in-Class (FIC) CDK2/4/6 inhibitor globally.
The world's first CDK2/4/6 inhibitor, developed by Chia Tai Tianqing Pharmaceutical Group, a subsidiary of Sino Biopharmaceutical, was officially approved for market launch on Thursday. CDK2/4/6 ...
... (CDK2) selective inhibitor ... “CDK2 has emerged as an important resistance mechanism in patients with HR+/HER2- breast cancer, especially for patients who progress on CDK4/6 inhibitors,” said Alberto J.
Eilean plans to present the drug candidate data at AACR-NCI-EORTC InternationalConference on MolecularTargets and Cancer Therapeutics and to advance this highly selective CDK2 inhibitor into a First-in-Human clinical study in Q4 2025.