Latest News for: ctla-4

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CStone Announces FDA Clearance of IND Application for Its Novel Trispecific Antibody CS2009 (PD-1/VEGF/CTLA-4) to Advance into Phase II Clinical Trial

PR Newswire 16 Feb 2026
CS2009 (PD-1/VEGF/CTLA-4 trispecific antibody) has received Investigational New Drug (IND) clearance from the U.S ... About CS2009 (PD-1/VEGF/CTLA-4 Trispecific Antibody).
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Preclinical Results of the Anti-CTLA-4 Switch Antibody ROSE12 Published in the Journal for ImmunoTherapy of Cancer (Chugai Pharmaceutical Co Ltd)

Public Technologies 28 Jan 2026
Preclinical Results of the Anti-CTLA-4 Switch Antibody ROSE12 Published in the Journal for ImmunoTherapy of Cancer ... ROSE12 binds to CTLA-4 in the presence of ATP, exhibits antibody-dependent cellular cytotoxicity (ADCC) activity, and depletes Tregs.
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Immuthera Announces Global Exclusive License from City of Hope for First-in-Class CD6/CTLA-4 CAR-Treg Platform for Autoimmune and Inflammatory Diseases

Pharmiweb 13 Jan 2026
The first and only CAR-Treg in development with a CTLA-4 Treg specific signaling domain to enhance function ... It is also the only CAR-Treg currently in clinical development with a Treg specific (CTLA-4) signaling domain.
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China's First Domestic Anti-CTLA-4 Monoclonal Antibody, Innovent's TABOSUN® (Ipilimumab N01 Injection) Received NMPA Approval

Ravalli Republic 26 Dec 2025
TABOSUN® (ipilimumab N01 injection) has been approved in combination ...
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Cadonilimab (PD-1/CTLA-4) Receives FDA Clearance for Global Phase III First-Line Gastric Cancer Trial Versus Nivolumab

Auburnpub dot com 12 Dec 2025
... a first-in-class PD-1/CTLA-4 bispecific antibody.
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New Era of CTLA-4 Modulation (Agenus Inc)

Public Technologies 11 Dec 2025
). The New Era of CTLA-4 Modulators. Special Session with Industry. Early Pipelines of Biotech Companies. Steven J. O'Day, MD ... 1 ... Anti-CTLA-4 ... of CTLA-4 ... 2014 Blocking Distinct Pathways with CTLA-4 and PD-1 ... B7 CTLA-4. Anti-CTLA-4 ... CTLA-4 Blockade PD-1 Blockade.
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