Latest News for: MDS

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Rigel Presents Updated Data from the Ongoing Phase 1b Study Evaluating R289 in Patients with Lower-Risk MDS at the 67th ASH Annual Meeting and Exposition (Form 8-K) (Rigel Pharmaceuticals Inc)

Public Technologies 10 Dec 2025
"New therapies are needed for patients with transfusion dependent lower-risk MDS ... R289 was generally well tolerated across all dose groups in this heavily pre-treated lower-risk MDS patient population, the majority of whom were HTB at baseline.
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Halia Therapeutics Announces Positive Phase 2a Data for Ofirnoflast in Lower-Risk MDS at ASH 2025

Missoulian 09 Dec 2025
– New findings demonstrate a 72% HI-E response rate at Week 16 with meaningful hemoglobin improvement – ... .
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Correlation between Treatment-Emergent Cytopenias and Clinical Response with Imetelstat (IME) in Patients (Pts) with Lower-Risk Myelodysplastic Syndromes (LR-MDS): Analysis from the IMerge Trial (Geron Corporation)

Public Technologies 08 Dec 2025
ANC, absolute neutrophil count; LR, lower risk; MDS, myelodysplastic syndromes; RBC, red blood cell; TEAE, treatment-emergent adverse event; TI, transfusion independence ... IPSS low- or INT-1-risk MDS ... IPSS low- or INT-1-risk MDS.
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Faron Presents Updated BEXMAB Data at ASH 2025: Deep and Durable Responses in HR-MDS with Favorable Safety Profile

Pharmiweb 08 Dec 2025
TURKU, FI / ACCESS Newswire / December 8, 2025 / Faron Pharmaceuticals (HEL.FARON)(LSE.FARN) - Significant efficacy observed in TP53-mutated patients with a 70% complete remission rate in the frontline HR MDS.
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Long-Term Outcomes from Randomized, Double-Blind, Placebo-Controlled, Phase 3 IMerge Trial of Imetelstat for Lower-Risk Myelodysplastic Syndromes (LR-MDS) (Geron Corporation)

Public Technologies 08 Dec 2025
Imetelstat, a first-in-class telomerase inhibitor, was approved in the United States (US) and Europe for the treatment of adult patients with LR-MDS and RBC-TD anemia (defined in the US label as requiring ... IPSS low-risk or intermediate-1-risk MDS.
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Rigel Presents Updated Data from the Ongoing Phase 1b Study Evaluating R289 in Patients with Lower-Risk MDS at the 67th ASH Annual Meeting and Exposition (Rigel Pharmaceuticals Inc)

Public Technologies 07 Dec 2025
... R289 as a therapeutic for MDS and lower-risk MDS, the existence of patients with an unmet medical need for such therapy, and Rigel's ability to further develop its clinical stage product candidates.
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Rigel Presents Updated Data from the Ongoing Phase 1b Study Evaluating R289 in Patients with Lower-Risk MDS at the 67th ASH Annual Meeting and Exposition

PR Newswire 07 Dec 2025
... R289 as a therapeutic for MDS and lower-risk MDS, the existence of patients with an unmet medical need for such therapy, and Rigel's ability to further develop its clinical stage product candidates.
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Aggiornamento PT web based REBLOZYL MDS (Italian Medicines Agency)

Public Technologies 24 Nov 2025
) Si informano gli utenti dei Registri Farmaci sottoposti a Monitoraggio che, a seguito dell'entrata in vigore della Determina AIFA n ... n ... Attachments Original document Permalink. Disclaimer ... (noodl.
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SPECIAL REPORT: Alleged $1bn NestOil Debt: First Bank, Access Bank, Zenith Bank MDs Risk Imprisonment Over Disobedience to Court Order

This Day 24 Nov 2025
Nigeria . 49 seconds ago. Wale Igbintade ... The warnings were contained in a series of Form 48 Notices of Consequences of Disobedience to Court Order, issued in relation to an interim directive made on November 6, 2025, in Suit No. FHC/ABJ/CS/2369/2025 ... .
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Young Wall Street, pay attention: 5 new Goldman MDs share their best tips for getting ...

Business Insider 13 Nov 2025
These MDs sit across the global bank, from asset and wealth management to global investment research to mergers and acquisitions and private wealth.
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