BRUIN CLL-313 is the first prospective, randomized Phase 3 study examining the efficacy and safety of a non-covalent BTK inhibitor, pirtobrutinib, exclusively in patients with treatment-naïve CLL/SLL.
Approval is based on results from the BRUIN CLL-321 trial, the only randomized Phase 3 study in CLL/SLL in which all patients were previously treated with a covalent BTK inhibitor ...Lilly is studying Jaypirca in CLL/SLL in multiple Phase 3 studies.
Rise in SLL crimes in Nagaland... The report shows SLL crimes surged from 445 cases in 2021, 584 in 2022 and 849 cases in 2023, the report said ... The SLL crime rate for Nagaland was 38 per lakh population, still lower than the national average of 178.0.