Tmb

Vilastobart (anti-CTLA-4) in MSS mCRC Patients with High Plasma TMB ... Vilastobart Data in Patients with MSS mCRC and High Plasma TMB ... Clinical Perspectives on Plasma TMB Data and Opportunity in MSS mCRC ... Tissue-Based TMB Assays ... Plasma-Based TMB Assays.

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40% ORR in heavily pre-treated patients with MSS mCRC without liver metastases and with high plasma tumor mutational burden (TMB) (Form 8-K) (Xilio Therapeutics Inc)

Public Technologies 07 Nov 2025

• In patients evaluable for plasma TMB status, 62.5% were TMB-high. All responders who were evaluable for plasma TMB status were TMB-high, and the correlation between plasma TMB status and response was statistically significant (p=0.05).

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40% ORR in heavily pre-treated patients with MSS mCRC without liver metastases and with high plasma tumor mutational burden (TMB) (Form 8-K) (Xilio Therapeutics Inc)

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