The corticospinal tract is known to be a major neural tract for motor function in the human brain. Several studies have reported on injury of the corticospinal tract by transtentorial herniation ...

Recovery of the corticospinal tracts injured by subfalcine herniation: a diffusion tensor tractography study. Neural Regen Res. 2014;9 (12):1231-1233. Contact: Meng Zhao eic@nrren.org 86-138-049-98773 ...

In humans, the corticospinal tract extends from the cerebral cortex in the upper brain down into the spinal cord. "We humans use corticospinal axons for voluntary movement," said Tuszynski.

The corticospinal tract (CST) is extensively used as a model system for assessing potential therapies to enhance neuronal regeneration and functional recovery following spinal cord injury (SCI ...

Damage to the corticospinal tract, the main white matter region of the brain responsible for carrying movement-related information to the spinal cord, is the primary cause of motor function ...

Kaimeng Du et al. Pten Deletion Promotes Regrowth of Corticospinal Tract Axons 1 Year after Spinal Cord Injury. Journal of Neuroscience, July 2015 DOI: 10.1523/JNEUROSCI.3637-14.2015 ...

Abstract The corticospinal tract (CST) is the most important motor system in humans, yet robust regeneration of this projection after spinal cord injury (SCI) has not been accomplished. In murine ...

Individual corticospinal tracts had the same size and shape as the template, but retained their unique water-diffusion characteristics. Therefore, the scientists could calculate MD and FA in all 34 ...

Weakness in ataxic hemiparesis is caused by disruption of the corticospinal tracts, and the ataxia is attributed either to involvement of the frontopontocerebellar connections or to impaired position ...

Conditional gene deletion then validated a role for NFE2L2 (or NRF2), a master regulator of antioxidant response, in corticospinal tract regeneration.

This sagittal section shows the regeneration of mouse corticospinal tract axons (red) 7 months after Pten deletion was initiated in motor cortex. Pten deletion was initiated 1 year after spinal ...