All of Hertzfeldt's work has a poignancy to them. In that poignancy, there is a little goofiness, introspection, sentimentality, absurdism, even a little horror. ME, for some reason feels the most monochromatic. Emotionally speaking, ME feels like Hertzfeldt's most apocalyptic and all-encompassing work yet. Even the "nervous system person" walking awkwardly through lava doesn't feel goofy. It feels too evocative, - that stripped down, naked, hunk of electrical signals bound together by screens - too dark.
That's why in more ways than one, this is also Don Hertzfeldt's best. Whatever the baby eye represents, I think there is a very eerie feeling of darkness in infantilising, (as well as reconciling) the presence of a creature who continuously surveils (cue dystopia metaphor). So much good imagery that sticks in your heard with this. But hey that's true for "beautiful day", "world of tomorrow" too. I'm just gonna have to rewatch his old repertoire again I guess.