Roger Pryor is a doctor who has success 'curing' patients by lowering their body temperatures. He is urged to publish his results, but wants to know more about the work of a doctor who pioneered the science, then vanished ten years before. Pryor and his nurse/girlfriend Jo Ann Sayers set out to find the last known address of the doctor, Boris Karloff (who else?) to see if he left any notes behind. Not only do they find his notes, they find him..frozen in a room 91 steps (they counted) below his laboratory. They thaw him out, and he tells what happened a decade before..how 3 officials tried to stop him from using the technique on a wealthy citizen, and they all got trapped in the 'deep freeze'.
Oddly, none of them seem particularly surprised or upset (?) about their years on ice, but things get ugly fast; one man becomes very greedy concerning profits from the promising technique, and Karloff wants to continue experimenting on everyone else. It's a fun watch, but you can guess early on that Karloff is going to go completely off the deep end (only naive' Pryor and Sayers are very slow to catch on).