From 54:01 when Edgar is explaining the history of F. Vought to Homelander in the wide angle his blazer is unbuttoned. At 54:08, when the camera cuts to a narrower angle, his blazer is buttoned.
Company founder Frederick Vought was supposedly so far "ahead of his time" in molecular genetics that he was able to develop Compound V even before World War II broke out. Quite a feat, considering that Watson and Crick only managed to decode the molecular structure of DNA in 1953; that it took a full 50 more years to just fully sequence a human genome for the first time; and that its workings are not fully understood to this day. It's like building an atomic bomb without knowledge about radioactivity and the structure of atoms (which is obviously not possible).