What a bizarre movie! Scream and Scream Again is all over the place. It's a combination horror/sci-fi/mystery/espionage/thriller with sort of a James Bond twist. And it's a lot of fun.
To be honest, at the beginning of the film, I was lost. There are about four different plot lines that don't seem to have anything to do with each other. (1) There is a runner who collapses. Every time we see him after the collapse, he's in a hospital losing his limbs one at a time. (2) There is a vampire killer on the prowl in London. He attacks young women and drains them of their blood. (3) There are scenes of some fascist regime in some unknown country. The leaders of the regime are being killed one at a time. Also, people are being tortured for no apparent reason. (4) There are discussions going on in the uppermost levels of the British government that appear to have nothing to do with anything else. But, by the end of the film, most everything fits together quite nicely as a story about creating a master race.
Scream and Scream Again 'stars' Vincent Price, Christopher Lee, and Peter Cushing. I say 'stars' because Christopher Lee and Peter Cushing are barely in the movie. In fact, Cushing has all of about 5 minutes of screen time. Alfred Marks as Supt.Bellaver is actually the star. He's a no nonsense policeman investigating the string of murders in London. In the end though, Price takes over and is wonderful. His mad doctor routine is terrific to watch.
There are some excellent moments in the film worth mentioning. The chase scene is one of the longest I've ever seen, ending with the killer losing a hand after being handcuffed to the front of a car. Another is the fight scene at the end between Vincent Price and leader of the fascists. There are also moments of tension as when the young doctor is snooping around Vincent Price's house.
This is a movie that you have to be patient with. Trust me, it all makes sense in the end.
