Satan Met a Lady is a fascinating adaptation of Dashiell Hammett's novel The Maltese Falcon into an unusual mixture of mystery and comedy and actually has several funny moments but veers so far from the source material that its effect is dissipated. In comparison to some recent comedy thrillers the film could be seen as ahead of its time. If John Huston had never made the quintessential Film Noir adaption of Hammet's novel The Maltese Falcon with Humphrey Bogart in the lead, Satan Met a Lady may have gained an entirely different stature.
The film does have some funny moments as when Valerie Purvis catches Shayne searching her room and pulls a gun on him with the line "Do you mind very much, Mr. Shayne, taking off your hat in the presence of a lady with a gun?" There is also some very funny stuff with Warren William playing against Arthur Treacher's British character Anthony Travers. When Travers says he'll give Shayne 500 dollars for information and hands him a bill, the detective walks over to a lamp inspects the bill and summarily tears it up, getting a gentlemanly response from the Brit in an "Sorry" as he hands him another bill which the private dick inspects and pockets- it's a bit of visual business that is perfectly timed by the actors.