Holliday's success as the brassy, cynical, gregarious Flo on
Alice (1976) (for which role she wore a red wig) reportedly did not endear her to the titular star of the show,
Linda Lavin. The friction between the two actresses was such that Holliday left for her own short-lived spin-off series,
Flo (1980).
Alice (1976) remained on the air for several more seasons but Holliday never returned, even to make a guest appearance. Holliday's successor, actress Diane Ladd (who had played "Flo" in the film
Alice non abita più qui (1974), on which the television series was based but adopted the role of "Belle Dupree" for the series), also did not get along with Lavin, and left. Ladd was succeeded by
Celia Weston, who remained until the series ended. Both Holliday and Ladd were both unsuccessfully nominated for the highest awards in their respective media for playing "Flo": Ladd for the Oscar and Holliday for an Emmy.