The films major strength are the performances. The main characters feel well fleshed out and are more complicated. They have differing views on sexuality and life, and you can see their relationship working and failing in real life.
The majority of the accompanying cast, whilst primarily only serving the scene they're in are usually within a well written scenario that either aids the story or humour. However the men are usually depicted as largely braindead. This wouldn't be an issue if the protagonist wasn't supposed to be bisexual (however I will concede that may be the point, that she's only labelling herself as such due to social pressures. But if it is the film is too ambiguous).
The films humour is a bit hit and miss. The parts that miss are the cliche 'saying something semi-outlandish and then it's awkward' or 'making a snarky judgment on someone and then have them reveal how noble they are' but they worst jokes are they jabs at NYC hipsterdom, mainly because the film doesn't seem to have the self awareness to realise all the characters are those personalities. The humour that works (aside from the kids film) is when the characters are just talking and adds a great deal of authenticity to the film.
The story follows a scene pattern that becomes dull fairly quickly (bar/event, meet x, hookup, flashback), but is just clever enough and well written to keep you watching. It's also not that long.