- Studied architecture.
- Worked as a salesperson and model after her first marriage until she became a TV presenter.
- Former model.
- Lived with producer Daniel Écija for 15 years. The couple married in 2003 and split in May 2004.
- Sister Chus Rueda usually works as an stylist in the TV series Belén participates in.
- Her character in Los Serrano (2003), Lucía, died in the episode aired in Spain on 6 March 2007, when the actress decided to leave the series in order to join other projects.
- Made her stage debut in "Closer", playing Julia Roberts's character in the movie version (January 2007).
- Had three children with Daniel Écija: Belén Écija (b. 1994), María (b. 1996) and Lucía (b. 1998). María died of a heart disease as a baby.
- Good friends with Emilio Aragón.
- Her father worked as a civil engineer, her mother was a ballet instructor.
- After her first, brief marriage ended in 1987, she was married for one year to Daniel Ecija. She gave birth to three children, one of whom passed away at a young age.
- Played the same role, Clara Nadal, first in some episodes of Médico de familia (1995) and then as a regular character in Periodistas (1998).
- Worked with actor Jesús Bonilla in the TV-series Periodistas (1998) and then in Los Serrano (2003).
- Didn't appear in one season of Los Serrano (2003). while filming the film The Sea Inside (2004).
- One of her co-stars in Periodistas (1998), actress Alicia Borrachero, gave her the award as best Spanish actress for her role in the film The Sea Inside (2004), in the Spanish Goya Ceremony in 2005.
- She's not going to appear in some chapters of "Los Serrano" that will be aired on June, because she's going to film a new movie called "El orfanato". (May 2006)
- Before beginning her acting career, she worked in modeling and sales and briefly studied architecture.
- Fluent in italian.
- Has an older and a younger sister.
- Ex partner in Los Serrano, Antonio Resines has handed her her Fotogramas Award as the best cinema actress for her work in the film El Orfanato. (March 2008)
- Was formerly in a relationship with Roger Vincent (2009-2014).
- She starred in the Guillermo Del Toro-produced horror film Los Ojos de Julia (Julia's Eyes).
- Her role in Los Serrano (The Serranos) earned her TP de Oro, Fotogramas de Plata, and Spanish Actors Union award nominations.
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