- Partnered with Arthur M. Landau and created the Hollywood-based Landau-Small Talent Agency, which represented performers such as Lionel Barrymore and Hedda Hopper.
- In March 1934 it was reported that Edward Small had signed Lawrence Tibbett to star in five movies. Ultimately no films with Tibbett for Small were ever made.
- Two sons, Robert and Bernard Small, with actress Edna Small.
- Founded Edward Small Productions, a low-budget production company.
- Founded, with Joseph M. Schenck and Harry M. Goetz, Reliance Pictures in 1932.
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