- Owing to the fact that her father Claus Toksvig was covering the Apollo mission, at the moment when Neil Armstrong stepped onto the Moon, an 11-year-old Sandi was in Houston's Mission Control, holding the hand of Mr Armstrong's secretary.
- Spoke with a strong New York accent when she first came to the UK aged 13 and found nobody would talk to her. After six months at school Sandi decided to adopt an English accent to help her make friends and after watching the film Brief Encounter (1945) decided to try and emulate actress Celia Johnson's speaking voice.
- Has three children: two daughters, Megan (b. 1988) and Jesse (b. 1990), and one son, Theo (b. 1994), with former partner Peta Stewart (they separated in 1997). The children were carried by Stewart and conceived through artificial insemination by donor, Christopher Lloyd Pack, Roger Lloyd Pack's brother.
- Although born in Denmark, she grew up in the USA until, at the age of 14, she moved to the UK, where she has lived ever since.
- Lives on a houseboat in Wandsworth with wife Debbie.
- Having been raised in the United States, her English accent is actually a put on. She naturally speaks with a US accent.
- She was awarded the OBE (Officer of the Order of the British Empire) in the 2014 Queen's New Years Honours List for her services to Broadcasting. She is a comedienne, presenter, and author in London, England.
- Has a First Class Honours Degree in Archaeology and Anthropology from Girton College, University of Cambridge.
- In the Independent on Sunday [UK] 2006 Pink List, a list of the most influential gay men and women, Toksvig came #85, a new entry.
- Has an older brother Nick (journalist) and a younger sister Jennifer (writes musicals).
- Journalist and comedienne daughter of fellow journalist Claus Toksvig.
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