- Speaks German.
- Dyed and cut her naturally long strawberry-blonde hair black for her role as Raissa on the soap opera America (2005).
- Partner with the producer Pedro Buarque de Hollanda between 2001 and 2009. They lived together in Ipanema, Rio de Janeiro.
- Mother named Fátima, father named José Nuzzi Neto. They split when Mariana was 17.
- Spent a week in a nunnery before playing Celi in Andando nas Nuvens.
- Her father is an attorney.
- In Brazil, she is the voice of Sharon Spitz (TV Series: Braceface (2001).
- Her favorite sports include soccer, basketball, and capoeira (a Brazilian martial art).
- Has a younger brother named Rafael.
- She dubbed Abby Mallard in the Brazilian version of the movie Chicken Little.
- She has participated from two video clips, "Anna Julia" from the band Los Hermanos and "Ja e" from the singer Lulu Santos.
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