- Turned down an offer of one million dollars to pose nude for Playboy magazine in the early 1970s.
- She played the same character (Gloria Bunker Stivic) on three different series: All in the Family (1971), Archie Bunker's Place (1979) and Gloria (1982).
- Is the only one of the four cast members of All in the Family (1971) who did not hail from New York City.
- Daughter, Samantha Rader, graduated from Vassar College in June 2001 with a degree in Cognitive Science.
- Made her TV debut as a dancer on a Herb Alpert special.
- Sideline: primitive artist (watercolors, acrylics).
- She played Miss Lynch for three years in the touring company of "Grease".
- Was long-time TV spokesperson for the Christian Children's Fund, appearing in several extended public service spots for them through the 1980s.
- Performed as Matron Mama Morton in the musical "Chicago" in Kansas City.
- Played Mother Superior in "Nunsense", a comedic play about nuns.
- Played Miss Hannigan in "Annie" at the Reagle Players, Waltham MA. This production also starred Bob Fitch, who played Rooster Hannigan in the original Broadway cast in 1977.
- Best remembered by the public for her role as "Gloria" on All in the Family (1971).
- Performed in "The Fully Monty." Struthers played Jeanette Burmeister, an aging old broad who Sally says had an early career playing the piano for bands and musicals.
- She is a lifelong Democrat.
- She played Miss Hannigan in the 20th Anniversary revival of "Annie" from January to June of 1998.
- Ogunquit, Maine. Played the role of Louise Seger in "Always Patsy Cline" at the Ogunquit Playhouse.
- Reprised the role of Dolly Levi in Lyric Theatre of Oklahoma's production of "Hello Dolly!", Oklahoma City, Oklahoma.
- Played Dolly Levi in the Bloomington Civic Theater production of "Hello Dolly" in Bloomington, Minnesota.
- Reprised the role of Miss Hannigan from "Annie" at the Nevada Conservatory Theatre at the University of Nevada, Las Vegas.
- She has appeared in one film that has been selected for the National Film Registry by the Library of Congress as being "culturally, historically or aesthetically" significant: Five Easy Pieces (1970).
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